Key facts about Lansoprazole
What dosages is Lansoprazole available in?
Lansoprazole is available as a 15 mg and 30 mg oral capsule/disintegrating tablet.
What is Lansoprazole used for?
Lansoprazole is a proton pump inhibitor that is used for the following:
- Frequent heartburn (2 or more days a week) – OTC only
Stomach or duodenal ulcer - Lower the risk of duodenal ulcer caused by Helicobacter pylori (H. pylori) infection
- Lower the risk of stomach ulcer due to nonsteroidal anti-inflammatory drugs (NSAID)
- Other medical conditions that cause too much stomach acid (e.g., Zollinger-Ellison syndrome)
- Gastroesophageal reflux disease (GERD)
- Erosive esophagitis (EE)
How does Lansoprazole work?
Lansoprazole is a proton pump inhibitor (PPI). It blocks acid from getting “pumped” into the stomach. This helps relieve heartburn and other medical conditions that cause too much stomach acid.
How do I take Lansoprazole?
Lansoprazole is typically taken as 15 mg or 30 mg by mouth once daily.
Is it safe for me to take Lansoprazole?
Lansoprazole is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Lansoprazole Common Side Effects
Common side effects of Lansoprazole:
- Diarrhea
- Belly pain
- Nausea
- Constipation
Lansoprazole Serious Side Effects
Serious side effects are rare with Lansoprazole. Serious Side Effects Contact your healthcare provider immediately if you experience any of the following.
- Severe stomach pain or diarrhea
- Kidney problems: urinating more or less than usual, fever, painful or difficult urination
- Lupus symptoms: joint pain, skin rash on arms or cheeks that gets worse in the sunlight
- Serious allergic reaction: blistering, peeling, or bleeding skin; fever; chills
Effects of other drugs, drug classes and over-the-counter products on Lansoprazole
The following medications may interact with Lansoprazole:
- Atazanavir: Do not co-administer with atazanavir.
- Drugs with pH-Dependent Absorption: May interfere with the absorption of drugs where gastric pH is important for bioavailability
- Warfarin: Concomitant warfarin use may require monitoring for increases in INR and prothrombin time.
- Tacrolimus: Concomitant tacrolimus use may increase tacrolimus whole blood concentrations
- Theophylline: Titration of theophylline dosage may be required when concomitant Lansoprazole use is started or stopped
- Methotrexate: Lansoprazole may increase serum levels of methotrexate
Who makes Lansoprazole?
Various FDA-approved generic manufacturers
Is Lansoprazole safe in pregnancy?
It is not known if Lansoprazole will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant.













