How can I lower the cost of my KOMBIGLYZE XR

You can lower cost of your KOMBIGLYZE XR using one of the 4 following drug savings programs: Rx Advantage Card for KOMBIGLYZE XR, Canadian Prescription Savings for KOMBIGLYZE XR, KOMBIGLYZE XR Drug Coupons, KOMBIGLYZE XR Patient Assistance Programs

KOMBIGLYZE XR Coupon, Savings Card and Patient Assistance

Home

Medications

KOMBIGLYZE XR

Used for Type 2 Diabetes

Are you tired of high medication costs? Our service offers unbeatable savings on your KOMBIGLYZE XR prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.

Manufactured by Bristol-Myers Squibb

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

This content is intended for US audiences only

Start Saving Today!

Lower the cost of your KOMBIGLYZE XR prescription

You can lower cost of your KOMBIGLYZE XR using one of the 4 following drug savings programs

Qualified
Rx Advantage Card
Save up to 90%

Check now
Available
Options*
Medication not available
N/A
Manufactured by
N/A
Powered by
Canadian Prescription Savings
Check eligibility
Unavailable
Drug Coupons
Unavailable
Available
Patient Assistance Programs
You can receive for FREE

Check now

scrollable

KOMBIGLYZE XR Uses, Side Effects, Interactions, Warnings & Dosing

Medically reviewed by Jamie Winn, Pharm.D

Written by Rajive Patel, B.Pharm

What is KOMBIGLYZE XR?

KOMBIGLYZE XR is the brand name for saxagliptin and metformin HCl and is available as an extended-release tablet.

What dosages is KOMBIGLYZE XR available in?

KOMBIGLYZE XR is available as an extended-release tablet that contains one of the following combinations:

5 mg saxagliptin/500 mg metformin HCl
5 mg saxagliptin/1000 mg metformin HCl
2.5 mg saxagliptin/1000 mg metformin HCl

What is KOMBIGLYZE XR used for?

KOMBIGLYZE XR is a DPP4 inhibitor / Biguanide combination used to treat type 2 diabetes.

How does KOMBIGLYZE XR work?

KOMBIGLYZE XR is a combination of metformin (a biguanide) and saxagliptin (a DPP4 inhibitor). KOMBIGLYZE XR works by lowering the amount of sugar made by your liver, decreasing the amount of sugar absorbed by your intestine, increasing the amount of insulin your body makes, and helps your body respond better to insulin.

How do I take KOMBIGLYZE XR?

The starting dose of KOMBIGLYZE XR depends on what medications you are currently taking for diabetes. Depending on how you respond, your healthcare provider will adjust your dose. The maximum dose for KOMBIGLYZE XR is 5 mg/2000 mg (saxagliptin/metformin) by mouth once daily with dinner.

Is it safe for me to take KOMBIGLYZE XR?

KOMBIGLYZE XR is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

Renal impairment
Hypersensitivity to metformin hydrochloride
Metabolic acidosis, including diabetic ketoacidosis
History of a serious hypersensitivity reaction (e.g., anaphylaxis, angioedema, exfoliative skin conditions) to KOMBIGLYZE XR or saxagliptin

KOMBIGLYZE XR Common Side Effects

Common side effects of KOMBIGLYZE XR:

Diarrhea
Nausea and vomiting
Headache
Upper respiratory tract infection (a viral infection that affects the nose, throat, and airways)
Bladder infection
Runny or stuffy nose and sore throat

KOMBIGLYZE XR Serious Side Effects

Serious side effects are rare with KOMBIGLYZE XR. Contact your healthcare provider immediately if you experience any of the following.

Build up of lactic acid in the blood (feeling of increased tiredness and weakness, stomach pain, muscle pain, increased sleepiness, breathing problems)
Signs of an allergic reaction like trouble breathing or swallowing, swelling (of your face, lips, tongue, or throat), peeling skin, rash, or hives
Inflammation of the pancreas (severe and persistent stomach pain, back pain, vomiting)
Heart failure (feeling out of breath, swelling of your feet, ankles or legs, fast increase in weight)
Large fluid-filled blisters on the skin

Effects of other drugs, drug classes and over-the-counter products on KOMBIGLYZE XR

The following medications may interact with KOMBIGLYZE XR:

Coadministration with strong CYP3A4/5 inhibitors (e.g., ketoconazole) significantly increases saxagliptin concentrations. Limit
KOMBIGLYZE XR dose to 2.5 mg/1000 mg once daily
Cationic drugs eliminated by renal tubular secretion may reduce metformin elimination: use with caution

Who makes KOMBIGLYZE XR?

Bristol-Myers Squibb

Is KOMBIGLYZE XR safe in pregnancy?

There are no adequate and well-controlled studies in pregnant women with KOMBIGLYZE XR or its individual components. Because animal reproduction studies are not always predictive of
human response, KOMBIGLYZE XR, like other antidiabetic medications, should be used during pregnancy only if clearly needed

What is the generic name for KOMBIGLYZE XR?

saxagliptin/metformin HCl extended-release

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects

Drug Savings Tips

How can NowPatient help me to lower the cost of my KOMBIGLYZE XR prescription?

How do the NowPatient KOMBIGLYZE XR savings programs work?

Are the NowPatient KOMBIGLYZE XR savings programs suitable for everyone, regardless of insurance status?

	Rx Advantage Card* for KOMBIGLYZE XR	Canadian Prescription Savings* for KOMBIGLYZE XR	KOMBIGLYZE XR Drug Coupon*	KOMBIGLYZE XR Patient Assistance Program*
Insured (federal, state or government)	Available	Available	Not Available	Available If Offered by Pharmaceutical Company
Insured (Commercial or Private)	Available	Available	Available If Offered by Pharmaceutical Company	Available If Offered by Pharmaceutical Company
Uninsured	Available	Available	Not Available	Available If Offered by Pharmaceutical Company
Insured but without pharmacy benefit or drug coverage	Available	Available	Not Available	Available If Offered by Pharmaceutical Company

Are the NowPatient drug savings programs suitable for brand and generic versions of KOMBIGLYZE XR?

	Rx Advantage Card* for KOMBIGLYZE XR	Canadian Prescription Savings* for KOMBIGLYZE XR	KOMBIGLYZE XR Drug Coupon*	KOMBIGLYZE XR Patient Assistance Program*
Brand	Yes	Yes	Yes, If Offered by Pharmaceutical Company	Yes, If Offered by Pharmaceutical Company
Generic	Yes	Yes	No	No

If you have Medicare Part D or Medicare Advantage and none of the KOMBIGLYZE XR savings options are applicable or affordable for me, what can you do?

I am uninsured or underinsured and none of the KOMBIGLYZE XR prescription saving options are applicable or affordable for me, what can I do?

I am commercially or privately insured and none of the KOMBIGLYZE XR prescription saving options are applicable or affordable for me, what can I do?

If I have federal, state or commercial insurance and none of the KOMBIGLYZE XR prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?

If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:

1. Patient Access Network Foundation (PAN) assistance for KOMBIGLYZE XR

If you are having trouble paying for your KOMBIGLYZE XR medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for KOMBIGLYZE XR you will need to meet one or all of the following criteria:

Your income is below 400% of the federal poverty level
KOMBIGLYZE XR is prescribed for an approved FDA indication
You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
You have Medicare insurance coverage that covers KOMBIGLYZE XR
If KOMBIGLYZE XR is listed on PAN’s list of covered medications

You can check the Patient Access Network Foundation Website for more information.

2. HealthWell Foundation Copay Program for KOMBIGLYZE XR

If you are having trouble paying for your KOMBIGLYZE XR medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for KOMBIGLYZE XR you will need to meet the following criteria:

You live in and are being treated in the United States
You are insured and your plan covers KOMBIGLYZE XR
If KOMBIGLYZE XR is listed on the HealthWell Foundation’s list of covered medications

You can check the HealthWell Foundation Website for more information.

3. Patient Advocate Foundation Co-Pay Relief Program for KOMBIGLYZE XR

Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your KOMBIGLYZE XR treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for KOMBIGLYZE XR you will need to meet the following criteria:

You must be currently insured and have coverage for KOMBIGLYZE XR
You must have a confirmed diagnosis and treatment plan
You must reside and receive treatment in the United States
Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.

You can check the Patient Advocate Foundation Website for more information.

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Data Security

Our Commitment to You.

Find out more

WHY WE BUILT NOWPATIENT

To improve the lives of everyone by making high-quality care accessible and convenient

We are here to improve lives. Our service gives you access to smart features and resources that can help empower you to take control of your health and improve your health outcomes. All this, in one place, for FREE. We strive to bring a fresh perspective to managing health. NowPatient can be accessed by downloading the App or using your web browser.