Used for Cancer

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

IMJUDO Uses, Side Effects, Interactions, Warnings & Dosing

What is IMJUDO?

What is IMJUDO?

IMJUDO is the brand name for tremelimumab-actl and is available as an IV infusion.

What dosages is IMJUDO available in?

What dosages is IMJUDO available in?

IMJUDO is available in the following:
25 mg/1.25 mL (20 mg/mL) solution in a single-dose vial.
300 mg/15 mL (20 mg/mL) solution in a single-dose vial.

What is IMJUDO used for?

What is IMJUDO used for?

IMJUDO is a CTLA-4 inhibitor that is used to treat the following:
Hepatocellular carcinoma (liver cancer) that can’t be removed with surgery, together with Imfinzi (durvalumab)
Metastatic non-small cell lung cancer without EGFR or ALK gene changes, together with Imfinzi (durvalumab) and platinum-based chemotherapy

How does IMJUDO work?

How does IMJUDO work?

IMJUDO is an immune checkpoint inhibitor (immunotherapy). More specifically, it’s an CTLA-4 inhibitor. By blocking CTLA-4, it helps the immune system detect and attack cancer cells.

How do I take IMJUDO?

How do I take IMJUDO?

Your provider will determine your IMJUDO treatment schedule based on the cancer type. You’ll also receive other medications, like Imfinzi (durvalumab) and/or chemotherapy, as part of your treatment plan, sometimes even on the days you’re not receiving IMJUDO.

Liver cancer (adults who weigh 66 lbs or more): The typical dose is 300 mg infused through the veins (IV) on Day 1 of your first treatment cycle only.

NSCLC (adults who weigh 66 lbs or more): The typical dose is 75 mg infused through the veins (IV) for a maximum of 5 doses.

Cycles 1 to 4: Once every 3 weeks during the first 4 treatment cycles.

Cycle 5: No IMJUDO infusion.

Cycle 6: Once on Day 1 of the 6th treatment cycle.

Your dose will be different if your body weight is less than 66 lbs.

Is it safe for me to take IMJUDO?

Is it safe for me to take IMJUDO?

IMJUDO is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

IMJUDO Common Side Effects

IMJUDO Common Side Effects

Common side effects of IMJUDO:

  • Abnormal liver labs
  • Lower blood cell counts
  • Lower blood sodium levels
  • Higher blood sugar
  • Lower blood calcium levels
  • Higher blood potassium levels
  • Abnormal kidney labs
  • Rash
  • Diarrhea
  • Fatigue
  • Itching
  • Muscle, bone, or joint pain
IMJUDO Serious Side Effects

IMJUDO Serious Side Effects

Serious side effects are rare with IMJUDO. Contact your healthcare provider immediately if you experience any of the following.

Immune-related adverse events: trouble breathing, cough, diarrhea, mucus or blood in the stool, stomach pain or cramps, rash
Infusion-related reactions: shortness of breath, itching, chills, flushing, upset stomach, or chest discomfort

Effects of other drugs, drug classes and over-the-counter products on IMJUDO

Effects of other drugs, drug classes and over-the-counter products on IMJUDO

There are no major drug interactions listed for IMJUDO. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Who makes IMJUDO?

Who makes IMJUDO?


Is IMJUDO safe in pregnancy?

Is IMJUDO safe in pregnancy?

IMJUDO can harm your unborn baby. Females who are able to become pregnant:
Your healthcare provider should do a pregnancy test before you start treatment with IMJUDO.
You should use an effective method of birth control during your treatment and for 3 months after your last dose of IMJUDO. Talk to your healthcare provider about birth control methods that you can use during this time.
Tell your healthcare provider right away if you become pregnant or think you may be pregnant during treatment with IMJUDO.


What to do if you missed your IMJUDO dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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