IMFINZI
Used for Cancer
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Manufactured by AstraZeneca
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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IMFINZI Uses, Side Effects, Interactions, Warnings & Dosing
What is IMFINZI?
IMFINZI is the brand name for durvalumab and is available as an IV infusion.
What dosages is IMFINZI available in?
IMFINZI is available in the following:
- 500 mg/10 mL (50 mg/mL) solution in a single-dose vial
- 120 mg/2.4 mL (50 mg/mL) solution in a single-dose vial
What is IMFINZI used for?
IMFINZI is a PD-L1 inhibitor that is used to treat:
Non-small cell lung cancer (NSCLC):
- Advanced NSCLC, after platinum-based chemotherapy and radiation
- Metastatic NSCLC without EGFR or ALK mutations, together with Imjudo (tremelimumab) and platinum-based chemotherapy
- Extensive-stage SCLC together with platinum-based chemotherapy
- Locally advanced or metastatic biliary tract cancer, together with gemcitabine (Gemzar) and cisplatin (Platinol)
- Advanced liver cancer together with Imjudo (tremelimumab)
How does IMFINZI work?
IMFINZI is an immune checkpoint inhibitor (immunotherapy) that blocks PD-L1. By blocking PD-L1, it takes the “brakes” off the immune system to detect and attack the cancer.
How do I take IMFINZI?
Your IMFINZI dose and schedule will depend on your cancer type. Depending on your cancer type, you might also receive other medications, like Imjudo (tremelimumab) and/or chemotherapy as part of your treatment plan.
For adults weighing 66 lbs or more:
- Advanced non-small cell lung cancer (NSCLC): The typical dose is 10 mg/kg every 2 weeks or 1,500 mg every 4 weeks as an infusion through the vein (IV). The maximum treatment time is 1 year
- Metastatic NSCLC: The typical dose is 1,500 mg every 3 weeks for 4 cycles, then 1,500 mg every 4 weeks as an infusion through the vein (IV)
- Small cell lung cancer (SCLC): The typical dose is 1,500 mg every 3 weeks for 4 cycles, then 1,500 mg every 4 weeks as an infusion through the vein (IV)
- Biliary tract cancers: The typical dose is 1,500 mg every 3 weeks for up to 8 cycles, then 1,500 mg every 4 weeks as an infusion through the vein (IV)
- Liver cancers: The typical dose is 1,500 mg every 4 weeks as an infusion through the vein (IV)
Your dose will be different if your body weight is less than 66 lbs.
Is it safe for me to take IMFINZI?
IMFINZI is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
IMFINZI Common Side Effects
Common side effects of IMFINZI:
- Higher blood sugar levels
- Lower blood calcium levels
- Lower white blood cell counts
- Cough
- Higher liver lab tests
- Trouble breathing and symptoms of lung inflammation
- Feeling very tired
- Lower blood sodium levels
- Higher blood potassium levels
- Sore throat, runny nose, and other symptoms of colds and sinus infections
- Trouble catching your breath
- Rash
IMFINZI Serious Side Effects
Serious side effects are rare with IMFINZI. Contact your healthcare provider immediately if you experience any of the following. Immune-related adverse events: diarrhea, stomach pain or cramps, blood or mucus in stool, rash, cough, trouble breathing Infusion-related reactions: shortness of breath, itching, chills, flushing, chest discomfort
Effects of other drugs, drug classes and over-the-counter products on IMFINZI
There are no major drug interactions listed for IMFINZI. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.
Who makes IMFINZI?
AstraZeneca
Is IMFINZI safe in pregnancy?
IMFINZI can harm your unborn baby. If you are able to
become pregnant, you should use an effective method of birth control during your treatment and for at least 3 months after the last dose of IMFINZI. Talk to your healthcare provider about birth control methods that you can use during this time. Tell your healthcare provider right away if you become
pregnant during treatment with IMFINZI.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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