HYQVIA
NowPatient helps you obtain your HYQVIA prescription for free or at low-cost. Drug savings programs are suitable for individuals who are insured, don't have insurance or are underinsured and can't afford your medicine.
Manufactured by Shire US Inc.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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HYQVIA key facts
What is HYQVIA?
HYQVIA is the brand name for immunoglobulin G with Recombinant Human Hyaluronidase and is available as a subcutaneous injection.
What dosages is HYQVIA available in?
HYQVIA A is a dual vial unit containing 100 mg/mL of Immune Globulin Infusion 10% (Human) and 160 U/mL of rHuPH20. HYQVIA is available in the following vial volumes: 25 mL, 50 mL, 100 mL, 200 mL and 300 mL.
What is HYQVIA used for?
HYQVIA is an immune globulin and is used for the following:
Primary humoral immunodeficiency or PI (a condition that makes you have trouble fighting infections) in people 2 years and older Chronic inflammatory demyelinating polyneuropathy or CIDP (a condition that causes nerve damage) in adults
How does HYQVIA work?
HYQVIA contains two components. Immunoglobulin G (IgG) — the main component of the medication — is a type of antibody that your immune system makes to help you fight off things that can make you sick (e.g., viruses, bacteria). With PI or CIDP, part of your immune system is either missing or isn’t working like it should. For PI, problems with the immune system can lead to frequent infections. HyQvia is thought to replace IgG and boost your immune system to help prevent infections. For CIDP, a dysfunctional immune system can lead to nerve damage. HyQvia thought to prevent an overly active immune system from attacking your nerves. Recombinant human hyaluronidase (HY) is a protein that helps your body absorb the medication better when it’s injected under the skin.
How do I take HYQVIA?
HYQVIA is given as an injection under the skin of the stomach or thighs using an infusion pump.
PI:
- Your dose depends on your body weight, the IgG levels in your blood, and whether you were previously using another immune globulin therapy
- You’ll start at a low dose, and then ramp up your dose over the first 7 weeks of treatment. You’ll typically infuse the medication once during weeks 1, 2, 4, and 7. Then, you’ll infuse HyQvia once every 3 to 4 weeks thereafter
- Your provider will adjust your dose based on how well HyQvia is working for you and whether you’re having side effects. Your dose might also differ if you’ve been exposed to measles or if you’re at risk of measles exposure (e.g., traveling to certain places)
CIDP:
- Your HyQvia dose depends on the dose of your previous intravenous immune globulin (IVIG) therapy
- Your first dose of HyQvia will be 2 weeks after your last IVIG dose. You’ll start HyQvia at a low dose and then ramp up your dose over several weeks of treatment (can take up to 9 weeks). Then, you’ll infuse HyQvia once every 3 to 4 weeks thereafter
- Your provider will adjust your dose based on how well HyQvia is working for you and whether you’re having side effects
Is it safe for me to take HYQVIA?
HYQVIA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have any of the following:
Severe allergy to immunoglobulin G, hyaluronidase, or human albumin. Immunoglobulin A deficiency with antibodies against IgA and a history of allergic reaction to immune globulin.
HYQVIA Common Side Effects
Common side effects of HYQVIA:
- Infusion-site reactions
- Headache
- Feeling tired
- Fever
HYQVIA Serious Side Effects
Serious side effects are rare with HYQVIA. Contact your healthcare provider immediately if you experience any of the following.
- Blood clots: in the lungs (cough, difficulty breathing, chest pain); in the leg (redness, pain, tenderness, swelling of the skin); near the heart (chest pain, pain in the arms or shoulders, pain in the neck or jaw); in the brain (difficulty speaking, numbness on one side of the body, confusion)
- Serious allergic reaction: difficulty breathing, tightness in the throat, hives, fast heartbeat, dizziness, lightheadedness, swelling in the face or tongue
- Brain inflammation: severe headache, neck stiffness, sensitivity to light, painful eye movements
- Kidney problems: tiredness, dry and itchy skin, low appetite, urinating less than usual, foamy or bloody urine, muscle cramps
- Breakdown of red blood cells: tiredness, dizziness, weakness, yellowing of the skin or eyes, dark-colored urine
- Lung problems: severe breathing problems, wheezing or rattling while breathing, chest pain, fever
Effects of other drugs, drug classes and over-the-counter products on HYQVIA
The following medications may interact with HYQVIA:
- Passive transfer of antibodies may transiently interfere with the immune responses to live virus vaccines, such as measles, mumps, and rubella
Who makes HYQVIA?
Shire US Inc.
Is HYQVIA safe in pregnancy?
It is not known if HYQVIA can harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effects in the USDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my HYQVIA prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your HYQVIA prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient HYQVIA savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient HYQVIA savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for HYQVIA | Canadian Prescription Savings* for HYQVIA | HYQVIA Drug Coupon* | HYQVIA Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of HYQVIA?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for HYQVIA | Canadian Prescription Savings* for HYQVIA | HYQVIA Drug Coupon* | HYQVIA Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the HYQVIA savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the HYQVIA drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for HYQVIA, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the HYQVIA prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, HYQVIA is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed HYQVIA for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the HYQVIA prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the HYQVIA prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for HYQVIA
If you are having trouble paying for your HYQVIA medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for HYQVIA you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- HYQVIA is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers HYQVIA
- If HYQVIA is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for HYQVIA
If you are having trouble paying for your HYQVIA medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for HYQVIA you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers HYQVIA
- If HYQVIA is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for HYQVIA
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your HYQVIA treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for HYQVIA you will need to meet the following criteria:
- You must be currently insured and have coverage for HYQVIA
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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