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Humatrope is the brand name for somatropin and is available as a subcutaneous injection.

Humatrope is available as a 6 mg, 12 mg, or 24 mg subcutaneous injection.

Humatrope is a recombinant human growth hormone and is used for the following:

• Certain growth-related conditions in children (e.g., low growth hormone, Turner Syndrome, Prader-Willi Syndrome)
• Low growth hormone in adults

Humatrope is a recombinant human growth hormone medication. It acts like our body’s natural growth hormone to promote growth in children. In adults, it helps control and maintain many important body functions, especially those that involve metabolism (how your body turns the food you eat into energy).

Somatropin injection is available as different brands:

• Genotropin, Humatrope, Norditropin, Nutropin AQ, Omnitrope, Saizen, and Zomacton
• Each brand contains a different amount of somatropin and has different administration instructions, so they are not interchangeable. Each brand also has specific dosing that’s based on the condition you’re being treated for. So, your provider will determine the right dose for you or your child
• Growth-related conditions in children: The dose is based on your child’s body weight. The medication is injected under the skin either 3, 6, or 7 days a week. How often your child needs medication depends on the condition your child has and the brand medication that’s used. If needed, your provider might adjust the dose based on how your child responds to the medication
• Low growth hormone in adults: There are two different ways the medication is dosed for adults. Some providers choose the dose based on your weight. Other providers might choose to start low and slowly raise the dose depending on how you respond to treatment. This medication is commonly injected under the skin once a day

Humatrope is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Acute critical illness
• Pediatric patients with Prader-Willi syndrome who are severely obese, have history of upper airway obstruction or sleep apnea, or have severe respiratory impairment due to risk of sudden death
• Active malignancy
• Hypersensitivity to somatropin or excipients
• Active proliferative or severe non-proliferative diabetic
  retinopathy
• Pediatric patients with closed epiphyses

Common side effects of Humatrope:

• Bruising
• Headache
• Leg pain
• Swelling in the arms and legs
• Joint pain
• Upper respiratory infections
• Pain in the arms and legs

Serious side effects are rare with Humatrope. Contact your healthcare provider immediately if you experience any of the following.

• Severe allergic reactions: skin rash, hives, itching, swelling of face or tongue, trouble breathing, chest tightness
• High blood pressure in the brain: changes in vision, headache, nausea, vomiting
• Swelling of the pancreas (pancreatitis): nausea, vomiting, severe abdominal pain that spreads to your back

The following medications may interact with Humatrope:

• Replacement Glucocorticoid Treatment: Patients treated with glucocorticoids for hypoadrenalism may require an increase in their maintenance or stress doses following initiation of Humatrope.
• Non-Replacement Glucocorticoid Treatment in Pediatric Patients: Adjust glucocorticoid dosing in pediatric patients receiving glucocorticoid treatment to avoid both hypoadrenalism and an inhibitory effect on growth.
• Cytochrome P450-Metabolized Drugs: Humatrope may alter the clearance. Monitor carefully if used with Humatrope
• Oral Estrogen: Patients may require larger doses of
• Humatrope
• Insulin and/or Other Hypoglycemic Agents: Dose adjustment of insulin or hypoglycemic agent may be required

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It is not known if Humatrope may harm your unborn baby. It should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

• Somatropin