gemfibrozil
Used for High Cholesterol
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Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
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gemfibrozil Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is gemfibrozil available in?
gemfibrozil is available as a 600 mg oral tablet.
What is gemfibrozil used for?
gemfibrozil is a fibrate that is used as an add-on to diet for the treatment of high triglycerides and to lower the risk of heart disease in people with low HDL, high LDL, and high triglycerides who’ve tried other options (e.g., exercise, other medications).
How does gemfibrozil work?
gemfibrozil is a fibrate. It works by helping to break down fats in your body. It also lowers the production of certain fats in your liver. This leads to the lowering of triglycerides (fats) and “bad” cholesterol (LDL) while raising “good” cholesterol (HDL) in the body.
How do I take gemfibrozil?
gemfibrozil is typically given as 600 mg by mouth twice daily, 30 minutes before breakfast and dinner.
Is it safe for me to take gemfibrozil?
gemfibrozil is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have hepatic or severe renal dysfunction, including primary biliary cirrhosis, preexisting gallbladder disease, a hypersensitivity to gemfibrozil or are taking simvastatin, repaglinide, dasabuvir, or selexipag.
gemfibrozil Common Side Effects
Common side effects of gemfibrozil:
- Indigestion
- Stomach pain
- Diarrhea
- Nausea or vomiting
- Constipation
gemfibrozil Serious Side Effects
Serious side effects are rare with gemfibrozil.
Effects of other drugs, drug classes and over-the-counter products on gemfibrozil
The following medications may interact with gemfibrozil:
- Warfarin – May result in a prolonged PT/INR time
- Immunosuppressants such as cyclosporine and tacrolimus – Can cause nephrotoxicity
- Bile acid binding resins: take gemfibrozil at least 1 hour before or 4 to 6 hours after a bile acid binding resin to avoid impeding its absorption
- Colchcine: Cases of myopathy, including rhabdomyolysis, have been reported with fenofibrates are taken with colchicine
- CYP2C8 Substrates: gemfibrozil is a strong inhibitor of CYP2C8 and may increase exposure of drugs mainly metabolized by CYP2C8 (e.g., dabrafenib, enzalutamide, loperamide, montelukast, paclitaxel, pioglitazone, rosiglitazone)
- HMG-CoA Reductase Inhibitors
- The concomitant administration of gemfibrozil with simvastatin, repaglinide, dasabuvir, or selexipag is contraindicated
Who makes gemfibrozil?
Various FDA-approved generic manufacturers
Is gemfibrozil safe in pregnancy?
There are no adequate and well-controlled studies in pregnant women. gemfibrozil should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
What is the brand name for gemfibrozil?
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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