FluconazolePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Fluconazole
    Generic for Diflucan
    30 tablets $12.3 USD
    Save $100.80
  3. Fluconazole
    Generic for Diflucan
    22 tablets $9 USD
    Save $73.94
  4. Fluconazole
    Generic for Diflucan
    82 tablets $27 USD
    Save $282.14
  5. Fluconazole
    Generic for Diflucan
    68 tablets $22.2 USD
    Save $234.16
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Do you need a prescription for fluconazole?

Yes, fluconazole is only available with a valid physician Rx.

How much is fluconazole without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase fluconazole, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for fluconazole in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a fluconazole savings card?

Yes. Save up to 90% on your fluconazole with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a fluconazole coupon provider in the US?

No. Now Patient does not provide fluconazole coupons or FREE fluconazole samples.

Do you accept commercial, Medicare or Medicaid coverage for fluconazole in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much fluconazole?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using fluconazole. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much fluconazole. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic fluconazole?

Generic fluconazole refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of fluconazole

Fluconazole is approved by the U.S. Food and Drug Administration (FDA) for the treatment of various fungal infections, including vaginal yeast infections, oral thrush, and systemic fungal infections.

Active ingredient of fluconazole

The active ingredient of fluconazole is fluconazole.

US brand name of fluconazole and manufacturer

Fluconazole is available in the US under various brand names, including Diflucan. The manufacturers may vary depending on the brand names.

UK brand name of fluconazole and manufacturer

In the UK, fluconazole is available under various brand names, including Diflucan and fluconazole. The manufacturer may vary depending on the brand name.

Prescription requirement for fluconazole

A prescription (Rx) is required for fluconazole in both the US and the UK.

Availability of fluconazole in the UK with NHS prescription

Fluconazole is available in the UK with an NHS prescription.

Conditions treated by fluconazole

Treatment of fungal infections is one of the primary uses of fluconazole. This antifungal medication, belonging to the class of azole antifungals, is effective against various types of fungal infections, including vaginal yeast infections (vaginal candidiasis), oral thrush, urinary tract infections and systemic fungal infections, affecting different parts of the body. Additionally, fluconazole is used to prevent candida infections in patients having bone marrow transplants who receive cancer or radiation treatment.

How does fluconazole work?

Fluconazole is in a class of antifungals called triazoles. It works by inhibiting the growth and spread of fungal cells by interfering with the synthesis of their cell walls, thereby killing or stopping the development of the fungi causing the infection.

Forms of fluconazole available

Fluconazole is available in various forms, including oral tablets, oral suspension, and intravenous (IV) injections.

Dosage of fluconazole

The dosage of fluconazole may vary depending on the specific fungal infection being treated, the severity of the infection, and other individual factors. It is important to follow the recommended dosage instructions provided by the healthcare provider.

If you miss a dose of fluconazole, take it as soon as you remember. If it is near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.

Directions for fluconazole use

Fluconazole should be taken as directed by the healthcare provider. The specific instructions may include the timing of administration, duration of treatment, and any necessary precautions.
Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Keep from freezing.

Warnings and precautions for fluconazole

  • Fluconazole may interact with other medications and substances, and dosage adjustments or close monitoring may be necessary
  • The drugs pimozide, clarithromycin, erythromycin, ranolazine, lomitapide, donepezil, voriconazole, and quinidine should not be used with fluconazole. These drugs can cause a life-threatening heart rhythm condition called torsades de pointes
  • Certain medical conditions, such as liver disease and heart rhythm disorders, may require special precautions or dosage adjustments when using fluconazole
  • It is important to inform a healthcare professional about all the medications you are currently taking, including prescription drugs, over-the-counter medications, vitamins, and herbal supplements. Some medications may interact with fluconazole and increase the risk of side effects or affect the effectiveness of either medication

Drug interactions

Precautions should be taken when taking fluconazole along with certain drugs:

  • Drug interactions can occur with medications such as cisapride, and pimozide, as they may increase the risk of serious cardiovascular effects
  • Fluconazole can also interact with certain medications that are metabolized by the liver, such as warfarin, phenytoin, and carbamazepine, potentially leading to increased levels of these drugs in the body
  • The risk of muscle pain or damage may increase with statins such as atorvastatin and simvastatin
  • Fluconazole may interact with medications used for QT prolongation, such as certain antiarrhythmics and antipsychotics, which can increase the risk of a life-threatening irregular heartbeat

Is fluconazole safe for pregnant women?

Before taking fluconazole in pregnancy and during breast feeding it is important to consult with a healthcare professional. While studies have not shown any increased risk of birth defects associated with fluconazole, caution is still advised. It is recommended to use the lowest effective dose for the shortest duration possible, as with any medication during pregnancy. Additionally, pregnant women with certain underlying health conditions or who are taking other medications should discuss the potential risks and benefits with their healthcare provider.

Possible side effects of fluconazole

The most common adverse effects of fluconazole include nausea, vomiting, diarrhea, stomach pain, and headache. These are usually mild and go away on their own. It is advisable to take the medication with food to minimize stomach discomfort.

In some cases, fluconazole may cause allergic reactions, such as hives, itching, swelling, dizziness, or difficulty breathing. If any of these symptoms occur, immediate medical attention should be sought.

Serious side effects are rare but can include liver damage, characterized by yellowing of the skin or eyes, dark urine, loss of appetite, unusual tiredness or persistent nausea. It is important to notify a healthcare professional if any signs of liver problems develop.

Similar drugs to fluconazole

Other antifungal medications, such as itraconazole and ketoconazole, may be used as alternatives to fluconazole to treat fungal infections.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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