View FLORINEF savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or FLORINEF Patient Assistance Program.

Programs are suitable for individuals who want to buy FLORINEF without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by Monarch Pharmaceuticals, Inc.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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    Save up to 90%

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about FLORINEF



FLORINEF is the brand name for fludricortisone and is available as an oral tablet.

What dosages is FLORINEF available in?

What dosages is FLORINEF available in?

FLORINEF is available as a 0.1 mg oral tablet.

What is FLORINEF used for?

What is FLORINEF used for?

FLORINEF is a corticosteroid that is used to treat Addison’s disease (adrenal insufficiency) and congenital adrenal hyperplasia (a genetic condition that affects hormone production).

How does FLORINEF work?

How does FLORINEF work?

FLORINEF is a corticosteroid. These are man-made steroids that are like cortisol, a natural hormone your body makes. It’s used to maintain the sodium, potassium, and water balance in your body.

How do I take FLORINEF?

How do I take FLORINEF?

FLORINEF is typically taken by mouth with dose ranges from 0.1 mg to 0.2 mg by mouth once daily. Your healthcare provider might adjust your dose based on your individual condition, side effects, and response to the medication.

Is it safe for me to take FLORINEF?

Is it safe for me to take FLORINEF?

FLORINEF is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have a systemic fungal infection and in those with a history of possible or known hypersensitivity to these agents.

FLORINEF Common Side Effects

FLORINEF Common Side Effects

Common side effects of FLORINEF include:

  • Swelling from fluids
  • High blood pressure
  • Muscle or bone weakness
  • Stomach pain
  • Slower wound healing
  • Thin, fragile skin
  • Headaches
  • Insomnia (trouble sleeping)
  • Changes in your mood
  • Headache
  • Weight gain
FLORINEF Serious Side Effects

FLORINEF Serious Side Effects

Serious side effects are rare with FLORINEF. Contact your healthcare provider immediately if you experience any of the following.

  • Severe allergic reaction: trouble breathing or swallowing, swelling (on your face, lips, mouth, or throat), peeling skin, rash, hives
Effects of other drugs, drug classes and over-the-counter products on FLORINEF

Effects of other drugs, drug classes and over-the-counter products on FLORINEF

The following medications may interact with FLORINEF:

  • Amphotericin B or potassium-depleting diuretics – May worsen hypokalemia
  • Digitalis glycosides – Increased risk of arrhythmias or digitalis toxicity associated with hypokalemia
  • Oral anticoagulants – Decreased prothrombin time response. Monitor prothrombin levels and adjust anticoagulant dosage accordingly
  • Antidiabetic drugs (oral agents and insulin) – Reduced antidiabetic effect. Monitor for symptoms of hyperglycemia; adjust dosage of antidiabetic drug upward if necessary
  • Aspirin – Increased ulcerogenic effect; decreased pharmacologic effect of aspirin
  • Barbiturates, phenytoin, or rifampin – Decreased levels and effects of FLORINEF
  • Anabolic steroids – Increased risk of edema.
  • Vaccines – Neurological complications and lack of antibody response
  • Estrogen – May increase the levels and effects of FLORINEF
Who makes FLORINEF?

Who makes FLORINEF?

Monarch Pharmaceuticals, Inc.

Is FLORINEF safe in pregnancy?

Is FLORINEF safe in pregnancy?

It is not known if FLORINEF will harm your unborn baby. Animal studies, however, suggest that excessive use of steroids can cause harm to unborn babies. You should talk to your healthcare provider before taking this medication if you are pregnant.


What to do if you missed your FLORINEF dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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