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Epivir-Hbv is the brand name for lamivudine and is available as an oral tablet and oral solution.

Epivir-Hbv is available as a 100 mg oral tablet and a 5 mg/mL oral solution.

Epivir-Hbv is an antiretroviral (ARV) used in the treatment of chronic hepatitis B virus infection associated with evidence of hepatitis B viral replication and active liver inflammation.

Epivir-Hbv is a nucleoside reverse transcriptase inhibitor (NRTI). It blocks an enzyme (protein) found in HIV and HBV called reverse transcriptase that usually helps the virus make copies of itself. By blocking reverse transcriptase, lamivudine (Epivir) prevents HIV and HBV from making copies of itself and spreading.

Epivir-Hbv is typically dosed as follows:

• Adults: The typical dose is 100 mg by mouth once daily.
• Children ages 2-17 years: Your child’s provider will determine the dose based on your child’s body weight. The typical dose is 3 mg/kg of body weight by mouth daily, up to a maximum of 100 mg.

Epivir-Hbv is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

• Previous hypersensitivity reaction
• To lamivudine

Common side effects of Epivir-Hbv:

• Ear, nose, and throat infections
• Sore throat
• Diarrhea

Serious side effects are rare with Epivir-Hbv. Contact your healthcare provider immediately if you experience any of the following:

• Serious liver problems: nausea, vomiting, not feeling hungry, pain in the right side of the stomach, yellowing of the whites of the eyes or skin, dark-colored urine, light-colored stool
• Too much lactic acid in the blood: weakness, tiredness, fast and shallow breathing, nausea, vomiting, fast heartbeat, confusion

The following medications may interact with:

• Sorbitol

GlaxoSmithKline

Limited studies showed that lamivudine didn’t raise the risk of birth defects if taken during pregnancy. HBV clinical guidelines recommend treatment for only certain pregnant people with hepatitis B. Talk to your doctor if you are already pregnant or if you have plans on becoming pregnant. They will recommend what is best for you. If you choose to take Epivir-Hbv during pregnancy, you’re encouraged to enroll in the Antiretroviral Pregnancy Registry (APR).

• Lamivudine