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Disopyramide Phosphate is available as a 100 mg and 150 mg extended-release oral capsule.

Disopyramide Phosphate is an antiarrhythmic ans is used to treat ventricular arrhythmias (a type of irregular heart rhythm).

Disopyramide Phosphate is an antiarrhythmic. It slows down abnormal electrical activity in your heart to treat irregular heart rhythm.

Disopyramide Phosphate is dosed as follows:

Immediate-release capsule (Norpace brand and generic)

• Adults: The typical dose is 150 mg by mouth every 6 hours
• Children: Your child’s dose will be based on their age and body weight. It’s typically given by mouth every 6 hours

Extended-release capsule (Disopyramide Phosphate brand)

• Adults: The typical dose is 300 mg by mouth every 12 hours
• Children: Ask your child’s provider if the extended-release version is right for your child

Your dose might differ if you weigh less than 110 pounds, have kidney or liver problems, or have certain specific heart problems. Your provider might adjust your dose if you experience side effects.

Disopyramide Phosphate is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. is contraindicated in the presence of cardiogenic shock, preexisting second-or third-degree AV block (if no pacemaker is present), congenital Q-T
prolongation, or known hypersensitivity to the drug.

Common side effects of Disopyramide Phosphate:

• Dry mouth
• Trouble starting to urinate or maintaining urine flow
• Constipation
• Blurred vision
• Dry nose, dry eyes, or dry throat
• Trouble urinating Frequent or urgent urination
• Nausea
• Pain, bloating, or gas
• Dizziness
• Fatigue or muscle weakness
• Headache
• Feeling unwell
• Aches or pains

Serious side effects are rare with Disopyramide Phosphate. Contact your healthcare provider immediately if you experience any of the following. Low blood pressure or abnormal heart rhythm: chest pain or discomfort, weakness, dizziness, fainting
Heart failure: shortness of breath, swelling of feet or ankles, sudden weight gain, dizziness

The following medications may interact with Disopyramide Phosphate:

• Although specific drug interaction studies have not been done, cases of life-threatening interactions
• have been reported for disopyramide when given with clarithromycin and erythromycin.

Various FDA-approved generic manufacturers

It is not known if Disopyramide Phosphate harms your unborn baby. Disopyramide Phosphate should be given to a pregnant woman only if clearly needed. Talk to your doctor about stopping Disopyramide Phosphate if you are pregnant or planning to become pregnant.

• Norpace CR