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dimethyl fumarate

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Is the cost of your dimethyl fumarate too expensive?

You may qualify for programs where you can pay as little as $0 per fill, subject to income and insurance status.

This content is intended for US audiences only

NowPatient offers cost effective access to dimethyl fumarate for everyone including those who are uninsured, those who have commercial insurance as well as those who are enrolled into state or federal programs like Medicaid, Medicare Part D, full Low Income Subsidy (LIS, “Extra Help”), TRICARE or Veterans (VA) Benefits.

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Table of contents
OverviewWhat can I do if I am commercially insured but cannot afford my dimethyl fumarate?What can I do if I am uninsured and cannot afford my dimethyl fumarate?What can I do if I am insured with Medicare and cannot afford my dimethyl fumarate?Am I eligible for the Rx Advantage Card and how much does dimethyl fumarate cost without insurance?What will my out-of-pocket cost be for dimethyl fumarate when using the Rx Advantage Card?Is it legal for me to pay cash for dimethyl fumarate even though I have insurance?Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?Does the Rx Advantage Card work with Commercial Insurance?How do I check prices for dimethyl fumarate and how do I use the Rx Advantage Card?Do I need to pay for the Rx Advantage Card?Is there a dimethyl fumarate co-pay program?Is there a dimethyl fumarate Patient Assistance Program (PAP)?What should I do if I take too much dimethyl fumarate?What are the benefits of NowPatient?What is generic dimethyl fumarate?FDA approval of dimethyl fumarateActive ingredient of dimethyl fumarateUS brand name of dimethyl fumarate and manufacturerUK brand name of dimethyl fumarate and manufacturerPrescription requirement for dimethyl fumarateAvailability of dimethyl fumarate in the UK with NHS prescriptionConditions treated by dimethyl fumarateHow does dimethyl fumarate work?Forms of dimethyl fumarate availableDosage of dimethyl fumarateDirections for dimethyl fumarate useWarnings and precautions for dimethyl fumarateUse of dimethyl fumarate during pregnancy and breastfeedingPossible side effects of dimethyl fumarateSimilar drugs to dimethyl fumarateSourcesPeople also asked
Navin Khosla NowPatientGreen tick
Medically reviewed by Navin Khosla, BPharm and written by Rajive Patel, BPharm - Updated on 25 Jan 2024
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What can I do if I am commercially insured but cannot afford my dimethyl fumarate?

If you are commercially insured and you cannot afford your copay or co-insurance you can opt for purchasing dimethyl fumarate outside of your plan using the Rx Advantage card, with costs that are usually lower than a typical plan copay. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

If you cannot afford the cash price possibly due to income constraints, then there is the option of applying to state assistance programs like Medicaid. Often, you may be able to receive your dimethyl fumarate without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am uninsured and cannot afford my dimethyl fumarate?

If you cannot afford the cash price of dimethyl fumarate using the Rx Advantage card then there is the option of applying to state programs like Medicaid. Often, you may be able to receive your dimethyl fumarate without any costs at all. You can check Medicaid eligibility in your state by following this link HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application.

What can I do if I am insured with Medicare and cannot afford my dimethyl fumarate?

If you are insured with Medicare and have Part D or an Advantage drug plan but cannot afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you have a number of options:

Option

Savings Information

RX ADVANTAGE CARD

You can use the Rx Advantage to purchase the medication outside of your plan at prices that may be lower than you copay or co-insurance element. If you elect to use this method, out of pocket costs do not contribute towards your plan deductibles.

LOW INCOME SUBSIDY

If this is still too expensive or unaffordable then you can apply for federal support like Low Income Subsidy (LIS). To be eligible for Low Income Subsidy, you need to be resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).

MEDICAID

Alternatively, you can check Medicaid eligibility in your state by following this link to the HealthCare.gov. The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.

Am I eligible for the Rx Advantage Card and how much does dimethyl fumarate cost without insurance?

Our website gives savings options to customers who wish to purchase dimethyl fumarate, as either a brand or generic, without the constraints of insurance. By using the Rx Advantage Card, users can save up to 90% on the cost of their medication. The card can be used at over 65,000 pharmacies nationwide, across America. Even if you are insured, in most cases the cash price will be significantly cheaper than your existing co-pay. NowPatient is able to negotiate discounts on bulk drug purchases with pharmacy owners meaning you can access lower medication prices at nearby pharmacies using our card that can be conveniently stored in your NowPatient account.

What will my out-of-pocket cost be for dimethyl fumarate when using the Rx Advantage Card?

Your out-of-pocket (OOP) cost will effectively be the discounted cash price you pay for dimethyl fumarate using the Rx Advantage Card. If you are insured, your OOP expense can not be used against your plan deductible, if your plan has a deductible.

Yes. The Rx Advantage card is especially useful for people who have High-deductible health plans (HDHPs). It can be used for insured, uninsured, and underinsured persons.

Does the Rx Advantage Card work with Medicare or any other federal or state insurance plans?

No. We do not bill any federal or state insurance including Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug benefit). When you purchase your medication using the NowPatient Rx Advantage Card, you will be doing so out of pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket dimethyl fumarate cash price you pay can be typically cheaper than your plan copay.

Does the Rx Advantage Card work with Commercial Insurance?

We do not bill your commercial insurance. When you purchase your medication using the Rx Advantage Card, from NowPatient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps in the event you have a plan with a deductible. The out-of-pocket dimethyl fumarate cash price you pay can be typically cheaper than your plan copay.

How do I check prices for dimethyl fumarate and how do I use the Rx Advantage Card?

You can search for the prices at nearby pharmacies using our website. Simply search your medication and enter your ZIP Code and we will show you the price of your drug at nearby pharmacies. If you are happy with the quote, you need to create an account with NowPatient and generate your card. Next, simply go to the pharmacy and fill your dimethyl fumarate Rx. Ask the pharmacy to run the card and check the price, even if they tell you they have another card they use. Your card is stored safely in your NowPatient account.

Do I need to pay for the Rx Advantage Card?

No. The Rx Advantage prescription savings card is FREE to use and store for NowPatient users.

Is there a dimethyl fumarate co-pay program?

Generic medications like dimethyl fumarate do not have co-pay card savings options. A Copay program, if available, would normally be for the brand name version of dimethyl fumarate. You can search the brand name of dimethyl fumarate and check to see if a co-pay program exists. Co-pay cards are programs run by pharmaceutical companies that offer you a direct way to lower your out-of-pocket costs for prescription drugs for eligible patients. The copay cards essentially allow physicians to prescribe medications that are clinically preferred.

Is there a dimethyl fumarate Patient Assistance Program (PAP)?

Generic medications like dimethyl fumarate do not have PAP savings options. A Patient assistance program, if available would normally be for the brand name version of dimethyl fumarate. You can search the brand name of dimethyl fumarate and check to see if a co-PAP exists. PAPs are programs that are run and sponsored by pharmaceutical companies. They offer uninsured, insured, or underinsured individuals access to high-cost brand-name medications, which may otherwise be unaffordable.

What should I do if I take too much dimethyl fumarate?

Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using dimethyl fumarate. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you've used too much dimethyl fumarate. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.

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What is generic dimethyl fumarate?

Generic dimethyl fumarate refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of dimethyl fumarate

Dimethyl fumarate is approved by the U.S. Food and Drug Administration (FDA) for the treatment of multiple sclerosis (MS).

Active ingredient of dimethyl fumarate

The active ingredient of dimethyl fumarate is dimethyl fumarate (DMF).

US brand name of dimethyl fumarate and manufacturer

Dimethyl fumarate is available in the US under the brand name Tecfidera. It is manufactured by Biogen.

UK brand name of dimethyl fumarate and manufacturer

In the UK, dimethyl fumarate is available under various brand names, including Tecfidera. The manufacturer may vary depending on the brand name.

Prescription requirement for dimethyl fumarate

A prescription (Rx) is required for dimethyl fumarate in both the US and the UK.

Availability of dimethyl fumarate in the UK with NHS prescription

Dimethyl fumarate is available in the UK with an NHS prescription.

Conditions treated by dimethyl fumarate

Dimethyl fumarate is primarily used for the treatment of relapsing forms of multiple sclerosis (MS), including relapsing-remitting MS (relapsing-remitting multiple sclerosis or RRMS) and active secondary progressive MS.

How does dimethyl fumarate work?

One of the key components of dimethyl fumarate’s mechanism of action is its ability to activate a specific pathway called the Nrf2 pathway. Nrf2 is a protein that helps regulate the body’s antioxidant response and promotes the production of various protective enzymes. By activating this pathway, dimethyl fumarate helps to increase the antioxidant capacity of cells, which can help reduce oxidative stress and inflammation.
In addition to its effects on the Nrf2 pathway, dimethyl fumarate also has immunomodulatory properties. It is believed to work by suppressing the activity of certain immune cells, such as T cells and dendritic cells, which play a role in the inflammatory response. By reducing the activity of these cells, dimethyl fumarate can help decrease the production of pro-inflammatory molecules, thus reducing inflammation in the body.
Another mechanism by which dimethyl fumarate may work is by affecting the balance of immune cells in the central nervous system (CNS). In MS, the immune system mistakenly attacks the protective covering of nerve fibers in the CNS, leading to inflammation and damage. Dimethyl fumarate is thought to shift the balance of immune cells in the CNS, favoring the presence of regulatory T cells, which help suppress the immune response and reduce inflammation. This shift in the balance of immune cells is believed to contribute to the therapeutic effects of dimethyl fumarate in treating MS.

Forms of dimethyl fumarate available

Dimethyl fumarate is available in the form of a capsule, delayed release.

Dosage of dimethyl fumarate

The dosage of dimethyl fumarate may vary depending on the individual’s condition, medical history, and response to the medication. It is essential to follow the recommended dosage instructions and patient information provided by the healthcare provider.

Directions for dimethyl fumarate use

Dimethyl fumarate should be taken exactly as directed by the healthcare provider. The medication is usually taken orally, with or without food. It is important to swallow the capsules whole and avoid crushing or chewing them.
Store this medicine in the original container at room temperature, away from moisture, heat, and light.

Warnings and precautions for dimethyl fumarate

  • Dimethyl fumarate may cause certain side effects, including flushing, gastrointestinal symptoms, and a decrease in white blood cell counts. Regular blood tests and monitoring are necessary during treatment
  • Dimethyl fumarate can decrease the number of lymphocytes (a type of white blood cell) in the body. If you have a history of low lymphocyte counts (lymphopenia) or any condition that affects your immune system, such as HIV/AIDS, you should inform your doctor before starting DMF
  • Dimethyl fumarate can increase your chances of getting a rare viral brain infection called PML (progressive multifocal leukoencephalopathy)
  • If you have a weakened immune system due to conditions such as organ transplantation, cancer, or autoimmune diseases, DMF may not be suitable for you. It is important to discuss your medical history with a healthcare professional to determine if DMF is safe and appropriate
  • Inform the healthcare provider about all medications being taken, as dimethyl fumarate may interact with certain medications and cause adverse effects

Use of dimethyl fumarate during pregnancy and breastfeeding

The use of dimethyl fumarate during pregnancy and breastfeeding should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider. It is important to balance the potential benefits of treatment with the potential risks to the fetus or the infant.

Possible side effects of dimethyl fumarate

In clinical trials common side effects of dimethyl fumarate may include flushing, stomach upset, abdominal pain, loss of appetite, diarrhea, and headache. Serious side effects are rare but may include allergic reactions or liver problems. Promptly report any concerning symptoms to a healthcare provider.

Similar drugs to dimethyl fumarate

Other medications used for the treatment of multiple sclerosis include interferon beta, glatiramer acetate, and natalizumab.

Sources

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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