Used for Birth Control

View dienogest savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or dienogest Patient Assistance Program.

Programs are suitable for individuals who want to buy dienogest without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by various FDA-approved generic manufacturers.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

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    Save up to 90%

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Updated on 24 Apr 2024

Learn more about dienogest

What dosages is dienogest available in?

What dosages is dienogest available in?

dienogest is available as a 2 mg oral tablet.

What is dienogest used for?

What is dienogest used for?

dienogest is indicated in the long-term treatment of endometriosis in adolescents from 12 years of age onward and adults.

How does dienogest work?

How does dienogest work?

dienogest belongs to the class of medications called progestins
Progestins reduce the effects of estrogen on tissues such as the endometrium (lining of the uterus) and the breast. By reducing the growth effect of estrogen on the endometrium, dienogest helps to reduce the pelvic pain experienced by women with endometriosis.

How do I take dienogest?

How do I take dienogest?

dienogest should start on day 1 of the woman’s natural cycle (i.e. the first day of her menstrual bleeding). The dosage of dienogest is one tablet daily without any break, taken preferably at
the same time each day with some liquid as needed. Tablets must be taken throughout 28 days without regard for bleeding. When a pack is finished the next one should be started without interruption

Is it safe for me to take dienogest?

Is it safe for me to take dienogest?

dienogest is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:

  • History of or active venous thromboembolic disorder.
    Arterial and cardiovascular diseases, past or present (e.g. myocardial infarction, cerebrovascular events,
    ischaemic heart disease)
  • Diabetes mellitus with vascular involvement
  • Presence or history of severe hepatic disease as long as liver function values have not returned to normal.
    Presence or history of liver tumours (benign or malignant)
  • Known or suspected sex hormone-dependent malignancies
  • Undiagnosed vaginal bleeding
  • Hypersensitivity to the active substance or to any of the excipients
dienogest Common Side Effects

dienogest Common Side Effects

Common side effects of dienogest:

  • Weight change
  • Increased appetite
  • Depressed mood
  • Sleep disorder
  • Nervousness
  • Loss of libido
  • Mood altered
  • Anxiety
  • Depression
  • Mood swings
  • Headache
  • Migraine
  • Dry eyes
  • Palpitations
  • Hypotension
  • Shortness of breath
  • Nausea
  • Abdominal pain
  • Flatulence
  • Abdominal distention
  • Vomiting
dienogest Serious Side Effects

dienogest Serious Side Effects

Serious side effects are rare with dienogest.

Effects of other drugs, drug classes and over-the-counter products on dienogest

Effects of other drugs, drug classes and over-the-counter products on dienogest

The following medications may interact with dienogest:

  • Progestogens, including dienogest, are metabolised mainly by the cytochrome P450 system (CYP3A4) Therefore, inducers or inhibitors of CYP3A4 may affect the drug metabolism of dienogest
  • An increased clearance of sex hormones due to enzyme induction may reduce the therapeutic effect of
  • dienogest and may result in undesirable effects e.g. change in bleeding profile
  • A reduced clearance of sex hormones due to enzyme inhibition may increase the therapeutic effects of dienogest and may result in undesirable effects
  • Substances increasing the clearance of sex hormones (diminished efficacy by enzyme-induction), e.g.: phenytoin, barbiturates, primidone, carbamazepine, rifampicin and possibly oxcarbazepine, topiramate felbamate, griseofulvin and products containing St. John’s wort
  • Enzyme induction can already be observed after a few days of treatment. Maximum enzyme induction is generally seen within a few weeks. After the cessation of drug therapy enzyme induction may be sustained for about 4 weeks
  • Substances with variable effects on the clearance of sex hormones, e.g.: When co-administered with sex hormones, many HIV/HCV protease inhibitors and non-nucleoside reverse transcriptase inhibitors can increase or decrease plasma concentrations of the progestin. These changes may be clinically relevant in some cases.
  • Substances decreasing the clearance of progestins (enzyme inhibitors) Dienogest is a substrate of cytochrome
  • Strong and moderate CYP3A4 inhibitors such as azole antifungals (e.g. itraconazole, voriconazole fluconazole), verapamil, macrolides (e.g. clarithromycin, erythromycin), diltiazem and grapefruit juice can increase plasma concentrations of the progestins.
Who makes dienogest?

Who makes dienogest?

Various FDA-approved generic manufacturers

Is dienogest safe in pregnancy?

Is dienogest safe in pregnancy?

There are limited data from the use of dienogest in pregnant women. Animal studies and data from women exposed to dienogest during pregnancy reveal no special risks on pregnancy, embryonic/ foetal development, birth or development after birth for humans. However, dienogest should not be administered to pregnant women because there is no need to treat endometriosis during pregnancy.


What to do if you missed your dienogest dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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