dabrafenib
Used for Cancer
Are you tired of high medication costs? Our service offers unbeatable savings on your dabrafenib prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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dabrafenib key facts
What dosages is dabrafenib available in?
dabrafenib is available as a 50 mg and 75 mg oral capsule and a 10 mg tablet for suspension.
What is dabrafenib used for?
dabrafenib is a kinase inhibitor that is used to treat:
- Melanoma with certain BRAF mutations
- Advanced melanoma, given after surgery and used with
- Mekinist (trametinib)
- Melanoma that has spread (metastatic) or can’t be removed by surgery, used alone or with Mekinist (trametinib)
- Metastatic non-small cell lung cancer (NSCLC) with a certain BRAF mutation, used with Mekinist (trametinib)
- Metastatic anaplastic thyroid cancer (ATC) with a certain BRAF mutation, used with Mekinist (trametinib)
- Solid tumors with a certain BRAF mutation that have spread (metastatic) or can’t be removed by surgery, used with Mekinist (trametinib)
- Low-grade glioma (LGG) with a certain BRAF mutation, used with Mekinist (trametinib)
How does dabrafenib work?
dabrafenib s a kinase inhibitor known as a BRAF inhibitor. The BRAF protein is part of a whole chain of proteins that help cells grow. When the BRAF protein is mutated, the cancer grows uncontrollably and can spread more quickly. By blocking BRAF, it helps stop tumor growth.
How do I take dabrafenib?
dabrafenib is dosed as follows:
- Adults: The typical dose is 150 mg by mouth twice a day (about 12 hours apart)
- Children: The dose is based on your child’s body weight. The typical dose ranges from 20 mg to 150 mg by mouth twice a day (about 12 hours apart)
Is it safe for me to take dabrafenib?
dabrafenib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
dabrafenib Common Side Effects
Common side effects of dabrafenib:
- High blood sugar
- Higher liver enzymes in the blood
- Fever
- Tiredness
- Changes in other blood test results
- Rash
- Nausea
- Headache
- Chills
- Diarrhea
- Vomiting
- Cough
- Muscle or joint pain
- Constipation
dabrafenib Serious Side Effects
Serious side effects are rare with dabrafenib. Contact your healthcare provider immediately if you experience any of the following.
- Bleeding: nosebleed, blood in stool, sudden and severe headache
- Serious eye problems: sudden and severe eye pain, sudden vision loss
- Serious skin reactions: painful blisters, skin wounds, peeling skin, fever, muscle aches
- Serious blood problems: fever, severe tiredness, weakness, trouble breathing
Effects of other drugs, drug classes and over-the-counter products on dabrafenib
The following medications may interact with dabrafenib:
- Avoid concurrent administration of strong inhibitors of CYP3A4 or CYP2C8
- Concomitant use with agents that are sensitive substrates of CYP3A4
- CYP2C8, CYP2C9, CYP2C19, or CYP2B6 may result in loss of efficacy of these agents
Who makes dabrafenib?
Various FDA-approved generic manufacturers
Is dabrafenib safe in pregnancy?
dabrafenib can harm your unborn baby.
Females who are able to become pregnant:
- Your healthcare provider will do a test to see if you are pregnant before starting treatment with dabrafenib
- You should use effective birth control (contraception) during treatment with dabrafenib and for 2 weeks after
your last dose of dabrafenib - Birth control methods that contain hormones (such as birth control pills, injections, or transdermal systems) may not work as well during treatment with dabrafenib and you could become pregnant. You should use another
effective method of birth control during treatment with dabrafenib - Talk to your healthcare provider about birth control methods that may be right for you during this time.
Tell your healthcare provider right away if you become pregnant or think you might be pregnant during treatment with dabrafenib - Males (including those who have had a vasectomy) with a female partner who is able to become pregnant:
- Use condoms during sexual intercourse during treatment with dabrafenib and for at least 2 weeks after your last dose of dabrafenib
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my dabrafenib prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your dabrafenib prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient dabrafenib savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient dabrafenib savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for dabrafenib | Canadian Prescription Savings* for dabrafenib | dabrafenib Drug Coupon* | dabrafenib Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of dabrafenib?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for dabrafenib | Canadian Prescription Savings* for dabrafenib | dabrafenib Drug Coupon* | dabrafenib Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the dabrafenib savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the dabrafenib drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for dabrafenib, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the dabrafenib prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, dabrafenib is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed dabrafenib for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the dabrafenib prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the dabrafenib prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for dabrafenib
If you are having trouble paying for your dabrafenib medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for dabrafenib you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- dabrafenib is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers dabrafenib
- If dabrafenib is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for dabrafenib
If you are having trouble paying for your dabrafenib medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for dabrafenib you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers dabrafenib
- If dabrafenib is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for dabrafenib
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your dabrafenib treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for dabrafenib you will need to meet the following criteria:
- You must be currently insured and have coverage for dabrafenib
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
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