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Crisaborole is available as a 2% topical ointment.

Crisaborole is a PDE4 inhibitor and is used to treat mild-to-moderate eczema.

Crisaborole is a phosphodiesterase4 enzyme (PDE4) inhibitor. PDE4 is a protein that controls inflammation in your body, and it’s more active in your skin cells when you have eczema. By blocking PDE4, Crisaborole helps treat eczema by lowering inflammation, itching, and redness.

Crisaborole is typically applied twice daily on any areas of your skin affected by eczema.

Crisaborole is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Crisaborole:

• Application site pain, burning, or stinging

Serious side effects are rare with Crisaborole. Contact your healthcare provider immediately if you experience any of the following.

Allergic reaction: itchy red rash (hives), shortness of breath, chest tightness, swelling of lips, tongue, or face

There are no major drug interactions listed for Crisaborole. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Various FDA-approved generic manufacturers

It is not known if Crisaborole can harm your unborn baby. Crisaborole should only be used during pregnancy if the benefit to you is worth the possible risk to your baby.

• Eucrisa