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Cozaar is the brand name for losartan potassium and is available as an oral tablet.

Cozaar is available as a 25 mg, 50 mg, and 100 mg oral tablet.

Cozaar is an ARB used to treat high blood pressure, to lower the risk of stroke in people with high blood pressure who have a thickened heart (left ventricular hypertrophy), and to slow down the worsening of kidney problems in people with Type 2 diabetes and high blood pressure.

Cozaar is an angiotensin II receptor blocker (ARB). The medication blocks a hormone that’s normally made in your body called angiotensin II from attaching to its receptors (signaling proteins) in your body. As a result, this helps lower your blood pressure in a few ways:

1. Relaxes your blood vessels so blood can flow through more easily

2. Stops your body from releasing aldosterone, a hormone that normally causes your body to hold onto water and affect blood pressure

3. Prevents your kidneys from absorbing water and salt (sodium) back into the body

Cozaar is typically taken by mouth once daily. The maximum recommended dose is 100 mg once daily.

Cozaar is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have diabetes and are taking aliskiren.

Common side effects of Cozaar include:

• Upper respiratory infection (e.g., common cold)
• Dizziness
• Stuffy nose
• Back pain
• Tiredness or sleepiness
• Headache
• Stomach pain
• Swelling in the hands or feet

Serious side effects are rare with Cozaar. Contact your healthcare provider immediately if you experience any of the following.

• Dangerously low blood pressure: dizziness, lightheadedness, pale skin, feeling faint
• Serious kidney problems: urinating less often than usual; swelling in your feet, ankles, or hands; unexplained weight gain
• High blood potassium levels: nausea, muscle weakness, abnormal heartbeat

The following medications may interact with Cozaar:

• Drugs that increase serum potassium – Risk of hyperkalemia
• Lithium – Risk of lithium toxicity
• NSAIDs – Increased risk of renal impairment and reduced diuretic, natriuretic, and antihypertensive effects
• Dual inhibition of the renin-angiotensin system – Increased risk of renal impairment, hypotension, syncope, and hyperkalemia

Merck & Co., Inc.

Cozaar may cause harm to your unborn baby. You should discontinue this medication immediately if you become pregnant.

• Losartan