ColesevelamPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Colesevelam HCl
    Generic for Welchol
    30 tablets $7.2 USD
    Save $82.50
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Do you need a prescription for colesevelam?

Yes, colesevelam is only available with a valid physician Rx.

How much is colesevelam without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase colesevelam, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for colesevelam in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a colesevelam savings card?

Yes. Save up to 90% on your colesevelam with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a colesevelam coupon provider in the US?

No. Now Patient does not provide colesevelam coupons or FREE colesevelam samples.

Do you accept commercial, Medicare or Medicaid coverage for colesevelam in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much colesevelam?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using colesevelam. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much colesevelam. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic colesevelam?

Generic colesevelam refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of colesevelam

Colesevelam is approved by the U.S. Food and Drug Administration (FDA) for the treatment of high cholesterol levels in adults.

Active ingredient of colesevelam

The active ingredient of colesevelam is colesevelam hydrochloride.

US brand name of colesevelam and manufacturer

Colesevelam is available in the US under the brand name Welchol. It is manufactured by Daiichi Sankyo.

UK brand name of colesevelam and manufacturer

In the UK, colesevelam is available under the brand name Cholestagel. The manufacturer may vary depending on the brand name.

Prescription requirement for colesevelam

A prescription (Rx) is required for colesevelam in both the US and the UK.

Availability of colesevelam in the UK with NHS prescription

Colesevelam is available in the UK with an NHS prescription.

Conditions treated by colesevelam

Colesevelam is primarily used for the treatment of high total cholesterol levels (hypercholesterolemia) in adults, particularly in those who have not responded well to lifestyle modifications or other cholesterol-lowering medications. It may also be used with diet and exercise to help control high blood sugar levels in adult patients with type 2 diabetes mellitus.

How does colesevelam work?

Colesevelam is a bile acid sequestrant that works in the intestines to bind to bile acids, preventing their reabsorption. By reducing the reabsorption of bile acids, colesevelam helps to lower LDL cholesterol levels in the blood.

Forms of colesevelam available

Colesevelam is available in the form of oral tablets or powder.

Dosage of colesevelam

The dosage of colesevelam may vary depending on the individual’s cholesterol levels and response to the medication. It is important to follow the recommended dosage instructions provided by the healthcare provider.

Directions for colesevelam use

Colesevelam HCL should be taken exactly as directed by the healthcare provider. The medication is usually taken with a meal or shortly after a meal. Colesevelam may be taken alone or in combination with other lipid lowering drugs such as statins to help reduce cholesterol levels.

Warnings and precautions for colesevelam

  • Colesevelam may interact with certain medications, including some oral contraceptives, blood thinners, and thyroid medications. Inform the healthcare provider about all medications being taken
  • Tell your doctor if you have, pancreatitis, high triglyceride levels, or gastrointestinal problems (such as constipation, blockage, bowel obstruction, or gastroparesis), phenylketonuria (PKU), or a history of vitamin A deficiency

Use of colesevelam during pregnancy

The use of colesevelam during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.

Use of colesevelam while breastfeeding

It is not known whether colesevelam passes into breast milk. The use of colesevelam while breastfeeding should be discussed with a healthcare provider.

Possible side effects of colesevelam

In clinical trials common side effects of colesevelam may include constipation, abdominal pain, indigestion, and nausea. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare provider. Get medical help right away if you have a life-threatening allergic reaction. Symptoms include hives, trouble breathing, shortness of breath, swelling of your face, tongue or throat, skin rash, and severe skin reactions. Promptly report any adverse events to a healthcare professional for medical advice.

Interactions with other drugs

Colchicine may interact with certain medications, including cyclosporine, glimepiride, glipizide, glyburide, metformin, olmesartan, phenytoin, pravastatin, levothyroxine, and warfarin. It is important to inform your healthcare provider about all the prescription drugs, non-prescription over the counter medication, supplements, and vitamins you are taking to avoid potential drug interactions.

Similar drugs to colesevelam

Other bile acid sequestrants used for the treatment of high cholesterol levels include cholestyramine and colestipol.


  • FDA Prescribing Information for Colesevelam
  • MHRA product information for Colesevelam
  • WebMD – Colesevelam
  • Drugs.com – Colesevelam
  • NHS UK


Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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