canagliflozin
Used for Type 2 Diabetes
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Manufactured by various FDA-approved generic manufacturers.
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canagliflozin Uses, Side Effects, Interactions, Warnings & Dosing
What dosages is canagliflozin available in?
canagliflozin is available as a 100 mg and 300 mg oral tablet.
What is canagliflozin used for?
canagliflozin is a SGLT2 inhibitor and is used for the following:
- Type 2 diabetes
- Lowering the risk of major heart events (e.g., heart attack, stroke) in adults with Type 2 diabetes and heart disease
- Lowering the risk of hospitalization for heart failure, death due to heart problems, and worsening of kidney problems in certain adults with Type 2 diabetes and diabetic kidney disease
How does canagliflozin work?
canagliflozin is a sodium-glucose cotransporter 2 (SGLT2) inhibitor. It works in the kidneys to prevent the absorption of sugar and sodium (salt) back into your body. It lowers blood sugar by causing your body to get rid of excess sugar through your urine. And by preventing sodium reabsorption, the heart fills with blood easier and has an easier time pumping blood throughout the body. This might also improve blood flow through the kidneys and slow the worsening of kidney problems.
How do I take canagliflozin?
- canagliflozin is typically started at 100 mg by mouth once daily before your first meal of the day. Your provider might raise your dose to 300 mg daily depending on how well the medication is working for you
- Your dose might differ if you have kidney problems. It also might differ if you’re taking certain medications like rifampin (Rifadin), phenytoin (Dilantin), phenobarbital, or ritonavir (Norvir)
Is it safe for me to take canagliflozin?
canagliflozin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you are on dialysis.
canagliflozin Common Side Effects
Common side effects of canagliflozin:
- Vaginal yeast infection in females
- Urinary tract infections
- More urination
canagliflozin Serious Side Effects
Serious side effects are rare with canagliflozin. Contact your healthcare provider immediately if you experience any of the following.
- Severe allergic reaction: rash; trouble breathing; swelling of the face, lips, tongue, or throat
- High ketone levels in the blood: nausea, vomiting, stomach pain, tiredness, thirsty, dry mouth, fruity breath, trouble breathing
Effects of other drugs, drug classes and over-the-counter products on canagliflozin
- The following medications may interact with canagliflozin:
- UGT enzyme inducers decrease canagliflozin exposure which may reduce the effectiveness of canagliflozin
- The risk of hypoglycemia is increased when canagliflozin is used concomitantly with insulin secretagogues (e.g., sulfonylurea) or insulin
- canagliflozin increases digoxin exposure
- Concomitant use of an SGLT2 inhibitor with lithium may decrease serum lithium concentrations
Who makes canagliflozin?
Various FDA-approved generic manufacturers
Is canagliflozin safe in pregnancy?
Based on animal data showing adverse renal effects from canagliflozin, INVOKAMET or canagliflozin is not recommended during the second and third trimesters of pregnancy.
What to do if you missed your canagliflozin dose
The FDA's medical product safety reporting program for health professionals, patients and consumers.
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Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
Things to know
What are the bad side effects of canagliflozin?
Does canagliflozin cause weight gain?
What is the black box warning for canagliflozin?
What does canagliflozin do to your body?
Can you lose weight with canagliflozin?
What is the controversy with Invokana?
How much weight can you lose on Invokana?
Can canagliflozin cause kidney damage?
Does Ozempic make you pee out sugar?
What are the precautions for canagliflozin?
Does canagliflozin affect blood pressure?
What kind of drug is canagliflozin?
What is the FDA warning on canagliflozin?
Does canagliflozin cause weight loss?
Is Invokana the same as metformin?
Why was Invokana taken off the market?
Is Invokana the same as Jardiance?
What is a good substitute for Invokana?
Is Invokana still available?
Why does canagliflozin cause amputations?
Is Farxiga similar to Invokana?
Is Invokana bad for kidneys?
Is Invokana a safe medication?
What is the difference between Januvia and Invokana?
Is canagliflozin better than metformin?
Who should not take canagliflozin?
Why is canagliflozin not used?
Is there a safer drug than metformin?
Can you take metformin and canagliflozin together?
What is the safest anti diabetic drug?
Why is Farxiga better than Jardiance?
Why is Jardiance better than metformin?
What lowers blood sugar better than metformin?
Does Jardiance work the same as Invokana?
What is the number one diabetic pill?
Which is better Farxiga or Invokana?
Which is better Ozempic or Invokana?
Which is better Farxiga or Invokana?
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