Used for Cancer

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Manufactured by AstraZeneca

*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.

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CALQUENCE cost saving options available to you

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    Drug Coupons

    Obtain your CALQUENCE for as little as $0 per fill. Suitable for insured individuals only.

    You can pay as little as $0

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    Obtain your CALQUENCE at no cost. Suitable for insured, underinsured and uninsured individuals

    You can receive for FREE


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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

CALQUENCE Uses, Side Effects, Interactions, Warnings & Dosing



CALQUENCE is the brand name for acalabrutinib and is available as an oral tablet.

What dosages is CALQUENCE available in?

What dosages is CALQUENCE available in?

CALQUENCE is available as a 100 mg oral tablet.

What is CALQUENCE used for?

What is CALQUENCE used for?

CALQUENCE is a kinas inhibitor that is used to treat:

  • Mantle cell lymphoma (MCL)
  • Chronic lymphocytic leukemia (CLL)
  • Small lymphocytic lymphoma (SLL)
How does CALQUENCE work?

How does CALQUENCE work?

CALQUENCE is a specific type of kinase inhibitor called a Bruton tyrosine kinase (BTK) inhibitor. BTK is a protein that helps MCL, CLL, and SLL cancer cells grow uncontrollably and survive. By targeting and blocking BTK, it stops cancer cell growth.

How do I take CALQUENCE?

How do I take CALQUENCE?

The typical starting dose of CALQUENCE is 100 mg taken by mouth twice a day (about 12 hours apart).

  • Your dose might be different if you experience certain side effects. It might also differ if you’re taking certain medications that might interact with CALQUENCE
Is it safe for me to take CALQUENCE?

Is it safe for me to take CALQUENCE?

CALQUENCE is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

CALQUENCE Common Side Effects

CALQUENCE Common Side Effects

Common side effects of CALQUENCE:

  • Anemia (low red blood cells)
  • Low white blood cells
  • Low platelets
  • Respiratory tract infection
  • Headache
  • Diarrhea
  • Muscle and joint pain
  • Tiredness
  • Rash
  • Nausea
  • Bruising
  • Bleeding
CALQUENCE Serious Side Effects

CALQUENCE Serious Side Effects

Serious side effects are rare with CALQUENCE. Contact your healthcare provider immediately if you experience any of the following.

  • Serious infections: body aches, chills, fever, headache, new cough, sore throat, feeling tired
  • Serious bleeding: bleeding or bruising that doesn’t stop or go away; large amount of bleeding; throwing up blood; blood in the urine; bloody or black, tarry stool
  • Heart rhythm problems: fast heartbeat, chest pain, fainting, dizziness, shortness of breath
Effects of other drugs, drug classes and over-the-counter products on CALQUENCE

Effects of other drugs, drug classes and over-the-counter products on CALQUENCE

The following medications may interact with CALQUENCE:

  • Strong CYP3A Inhibitors: Avoid co-administration with CALQUENCE
  • Moderate CYP3A Inhibitors: Reduce the dosage of CALQUENCE
  • Strong CYP3A Inducers: Avoid co-administration with CALQUENCE. If co-administration is unavoidable, increase the dosage of CALQUENCE
Who makes CALQUENCE?

Who makes CALQUENCE?


Is CALQUENCE safe in pregnancy?

Is CALQUENCE safe in pregnancy?

CALQUENCE may harm your unborn baby and cause problems during childbirth (dystocia). If you are able to become pregnant, your healthcare provider may do a pregnancy test before you start treatment with CALQUENCE. Females who are able to become pregnant should use effective birth control (contraception) during treatment with CALQUENCE and for 1 week after the last dose of CALQUENCE.


What to do if you missed your CALQUENCE dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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