BrimonidinePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
    You save
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  2. Brimonidine Tartrate
    Generic for Alphagan
    15mL ophthalmic solutions $7.78 USD
    Save $64.72
  3. Brimonidine Tartrate-Timolol 0.2%-0.5%
    Generic for Combigan
    5mL bottle of solutions $81.03 USD
    Save $123.72
  4. Brimonidine Tartrate-Timolol 0.2%-0.5%
    Generic for Combigan
    10mL bottle of solutions $159.05 USD
    Save $250.45
  5. Brimonidine Tartrate-Timolol 0.2%-0.5%
    Generic for Combigan
    15mL bottle of solutions $237.06 USD
    Save $377.19
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Do you need a prescription for brimonidine?

Yes, brimonidine is only available with a valid physician Rx.

How much is brimonidine without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase brimonidine, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for brimonidine in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a brimonidine savings card?

Yes. Save up to 90% on your brimonidine with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a brimonidine coupon provider in the US?

No. Now Patient does not provide brimonidine coupons or FREE brimonidine samples.

Do you accept commercial, Medicare or Medicaid coverage for brimonidine in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much brimonidine?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using brimonidine. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much brimonidine. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is Generic Brimonidine?

Generic Brimonidine refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of brimonidine

Brimonidine is approved by the U.S. Food and Drug Administration (FDA) for the treatment of glaucoma and ocular hypertension.

Active ingredient of brimonidine

The active ingredient of Brimonidine is brimonidine tartrate.

US brand name of brimonidine and manufacturer

Brimonidine is available under various brand names in the US, including Alphagan. These medications are manufactured by different pharmaceutical companies.

UK brand name of brimonidine and manufacturer

In the UK, Brimonidine is available under various brand names, and the manufacturers may vary.

Prescription requirement for brimonidine

A prescription (Rx) is required for Brimonidine in both the US and the UK.

Availability of brimonidine in the UK with NHS prescription

Brimonidine is available in the UK with an NHS prescription.

Conditions treated by brimonidine

Brimonidine is used to lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. It helps prevent damage to the optic nerve and vision loss associated with these conditions.

How does brimonidine work?

Brimonidine belongs to a class of medications called alpha-2 adrenergic agonists. It works by reducing the production of fluid inside the eye and increasing the drainage of fluid, which helps lower intraocular pressure.

Forms of brimonidine available

Brimonidine is available in the form of eye drops.

Dosage of brimonidine

The dosage of Brimonidine may vary depending on the specific condition being treated, the severity of the condition, and individual patient factors. It is important to follow the prescribed dosage instructions provided by the healthcare provider.

Directions for brimonidine use

Brimonidine eye drops should be used exactly as directed by the healthcare provider. Typically, one or two drops are instilled into the affected eye(s) two to three times daily. It is important to avoid touching the tip of the dropper to prevent contamination.

Warnings and precautions for brimonidine

  • Brimonidine may cause temporary blurred vision or drowsiness. It is important to assess your response to the medication before driving or operating machinery.
  • It may interact with certain medications, including other eye drops, blood pressure medications, and certain antidepressants. It is important to inform the healthcare provider about all medications being taken.

Use of brimonidine during pregnancy

The use of Brimonidine during pregnancy should be determined by the healthcare provider. Consultation is necessary to assess the potential risks and benefits in individual cases.

Use of brimonidine while breastfeeding

It is not known whether Brimonidine passes into breast milk. Consultation with a healthcare provider is necessary to discuss the potential risks and benefits in individual cases.

Possible side effects of brimonidine

Common side effects of Brimonidine may include eye redness, dryness or itching of the eyes, blurred vision, and allergic reactions. Serious side effects are rare but can include changes in heart rate or blood pressure and eye irritation.

Similar drugs to brimonidine

Other medications used to treat glaucoma and lower intraocular pressure include prostaglandin analogs, beta-blockers, and carbonic anhydrase inhibitors.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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