Key facts about Brentuximab Vedotin
What dosages is Brentuximab Vedotin available in?
Brentuximab Vedotin is available as 50 mg single-dose vial.
What is Brentuximab Vedotin used for?
Brentuximab Vedotin is an antibody-drug conjugate used to treat certain types of lymphoma.
How does Brentuximab Vedotin work?
Brentuximab Vedotin is a CD30-directed antibody and microtubule inhibitor conjugate. It works by targeting and binding to the CD30 protein on cancer cells, such as those in lymphomas. Once attached, the drug is brought into the cancer cell, where it releases a substance that stops the cell from growing and dividing, leading to its death.
How do I take Brentuximab Vedotin?
Your dose of Brentuximab Vedotin is based on your weight, what is being treated, and what other medications you are taking. It is given as an intravenous infusion over 30 minutes.
Is it safe for me to take Brentuximab Vedotin?
Brentuximab Vedotin is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication in the following:
- Concomitant use with bleomycin
Brentuximab Vedotin Common Side Effects
Common side effects of Brentuximab Vedotin:
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Abdominal pain
- Peripheral neuropathy (numbness, tingling, or pain in hands and feet)
- Headache
- Dizziness
- Fatigue
- Muscle aches
- Joint or bone pain
- Upper respiratory tract infections
- Fever
- Rash
- Hair loss
- Mouth sores
Brentuximab Vedotin Serious Side Effects
Serious side effects are rare with Brentuximab Vedotin. Contact your healthcare provider immediately if you experience any of the following:
- Allergic reactions
- Serious infections
- Tumor lysis syndrome
- LIver damage
- Serious skin reactions
- New or worsening breathing problems
Effects of other drugs, drug classes and over-the-counter products on Brentuximab Vedotin
The following medications may interact with Brentuximab Vedotin:
- CYP3A4 inhibitors or inducers
Who makes Brentuximab Vedotin?
Various FDA-approved generic manufacturers
Is Brentuximab Vedotin safe in pregnancy?
Brentuximab Vedotin can cause fetal harm. Women receiving this medication to use effective contraception during treatment and for 2 months after the last dose. Males with female sexual partners of reproductive potential to use effective contraception during treatment and for 4 months after the last dose.
