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Benralizumab is available as a 30 mg/mL solution in a single-dose prefilled syringe.

Benralizumab is an interleukin antagonist that is used as an add-on treatment for severe eosinophilic asthma in people 12 years and older.

Benralizumab is an interleukin antagonist. It blocks interleukin-5 (IL-5), a protein that normally makes white blood cells called eosinophils. Having high levels of eosinophils in the body can lead to inflammation, which plays a role in asthma. While the exact way Benralizumab works to treat asthma isn’t fully understood, it’s known that the medication reduces the level of eosinophils in the body. This is thought to lessen inflammation in the lungs, which helps to ease symptoms of severe asthma.

The typical starting dose of Benralizumab is 30 mg injected under the skin every month for the first 3 months. After that, the typical maintenance dose is 30 mg injected under the skin every 2 months.

Benralizumab is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

Common side effects of Benralizumab:

• Headache
• Sore throat
• Fever
• Injection site reaction (e.g., pain, redness, itching, raised skin)

Serious side effects are rare with Benralizumab. Contact your healthcare provider immediately if you experience any of the following.

• Serious allergic reactions: trouble breathing; rash; fever; swelling in your face, lips, or tongue; fast heartbeat, nausea, vomiting

There are no major drug interactions listed for Benralizumab. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking.

Various FDA-approved generic manufacturers

It is not known if Benralizumab will harm your unborn baby. Tell your healthcare provider if you become pregnant during your treatment with Benralizumab.

• Fasenra