View APIDRA savings options available to you including Manufacturer Coupons, Rx Advantage Savings Card, Canadian Prescription Savings or APIDRA Patient Assistance Program.

Programs are suitable for individuals who want to buy APIDRA without insurance, with insurance or for those who are underinsured. You can pay as little as $0 per fill.*

Manufactured by sanofi-aventis U.S.

*Applicable to Drug Coupons & Patient Assistance Programs

This content is intended for US audiences only

Drug savings programs

  • Qualified

    Rx Advantage Card

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    Save up to 90%

  • Unavailable

    Canadian Prescription Savings

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  • Available

    Drug Coupons

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    Pay as little as $0

  • Available

    Patient Assistance Programs

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Jamie Winn NowPatientGreen tick
Updated on 26 Apr 2024

Learn more about APIDRA

What is APIDRA?

What is APIDRA?

APIDRA is the brand name for insulin glulisine injection.

What dosages is APIDRA available in?

What dosages is APIDRA available in?

APIDRA 100 units/mL (U-100) is available as:

  • 10 mL vials
  • 3 mL cartridge system for use in OptiClik (Insulin Delivery Device)
What is APIDRA used for?

What is APIDRA used for?

APIDRA is an insulin that is available to treat:

  • Type 1 diabetes (adults and children age 4 years and older)
  • Type 2 diabetes (adults only)
How does APIDRA work?

How does APIDRA work?

APIDRA is an insulin, which is a natural hormone your body normally makes to lower glucose (sugar) levels in the blood. It helps your body absorb and store sugar from your bloodstream after eating a meal. It also stops your liver from making glucose.

How do I take APIDRA?

How do I take APIDRA?

Your healthcare provider will work with you to determine your dose of APIDRA. The dose of APIDRA will be different for each person. It depends on different factors such as, whether you have type 1 or type 2 diabetes, how well your body responds to insulin, and how you’re receiving this medication. Subcutaneous (SC) injection: APIDRA is typically injected under the skin within 15 minutes before a meal or within 20 minutes right after a meal. Continuous insulin pump: Refer to the instructions from your insulin pump manufacturer.

Is it safe for me to take APIDRA?

Is it safe for me to take APIDRA?

APIDRA is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have symptoms of low blood sugar.

APIDRA Common Side Effects

APIDRA Common Side Effects

Common side effects of APIDRA:

  • Type 1 diabetes
  • Common cold
  • Low blood sugar
  • Upper respiratory tract infection
  • Headache – children only
  • Seizure from low blood sugar – children only
  • Flu
  • Type 2 diabetes
  • Upper respiratory tract infection
  • Common cold
  • Swelling in the hands, ankles, or legs
  • Flu
  • Joint pain
APIDRA Serious Side Effects

APIDRA Serious Side Effects

Serious side effects are rare with APIDRA. Contact your healthcare provider immediately if you experience any of the following.

  • Severely low blood sugar: dizziness, shakiness, feeling confused, feeling irritable or anxious, feeling faint, sweating, extreme hunger
  • Ketoacidosis (high ketone levels in the blood): nausea, vomiting, stomach pain, tiredness, thirsty, dry mouth, fruity breath, trouble breathing
  • Severely low potassium levels: weakness, muscle cramps or twitches, constipation, abnormal heartbeat, nausea, vomiting
  • Severe allergic reactions: rash, hives, swelling of face, tongue, and throat, difficulty breathing
Effects of other drugs, drug classes and over-the-counter products on APIDRA

Effects of other drugs, drug classes and over-the-counter products on APIDRA

The following medications may interact with APIDRA:

  • Certain drugs affect glucose metabolism and may necessitate insulin dose adjustment
  • The signs of hypoglycemia may be reduced or absent in patients taking anti-adrenergic drugs (e.g., beta-blockers, clonidine, guanethidine, and reserpine).
Who makes APIDRA?

Who makes APIDRA?

sanofi-aventis U.S.

Is APIDRA safe in pregnancy?

Is APIDRA safe in pregnancy?

It is not known if APIDRA may harm your unborn baby. It is very important to maintain control of your blood sugar
levels during pregnancy. Your healthcare provider will decide which insulin is best for you during your pregnancy.


What to do if you missed your APIDRA dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Drug Savings Tips

Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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