AlendronatePrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Alendronate
    Generic for Fosamax
    9 tablets $6 USD
    Save $251.49
  3. Alendronate
    Generic for Fosamax
    17 tablets $11.7 USD
    Save $474.67
  4. Alendronate
    Generic for Fosamax
    30 tablets $18.6 USD
    Save $839.70
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Do you need a prescription for alendronate?

Yes, alendronate is only available with a valid physician Rx.

How much is alendronate without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase alendronate, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for alendronate in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a alendronate savings card?

Yes. Save up to 90% on your alendronate with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a alendronate coupon provider in the US?

No. Now Patient does not provide alendronate coupons or FREE alendronate samples.

Do you accept commercial, Medicare or Medicaid coverage for alendronate in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much alendronate?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using alendronate. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much alendronate. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is alendronate?

Alendronate is a medication used for the prevention and treatment of osteoporosis in postmenopausal women and men. It belongs to a class of drugs called bisphosphonates, which work by slowing down bone loss and increasing bone density.

FDA approval of alendronate

Alendronate is approved by the U.S. Food and Drug Administration (FDA) for the treatment and prevention of osteoporosis in postmenopausal women and men.

Active ingredient of alendronate

The active ingredient of alendronate is alendronate sodium.

US brand name of alendronate and manufacturer

Alendronate is available under various brand names in the United States, including Fosamax, Binosto, and alendronate sodium. These brand names are manufactured by different pharmaceutical companies.

UK brand name of alendronate and manufacturer

In the United Kingdom, alendronate is available under different brand names, including Fosamax and alendronic acid. These brand names are also manufactured by various pharmaceutical companies.

Generic availability of alendronate

Alendronate is available as a generic medication, which means it can be sold under its chemical name, alendronate, without a specific brand name.

Prescription requirement for alendronate

Alendronate is a prescription medication in the United States and the United Kingdom. It is important to consult a healthcare provider who can evaluate your condition and determine if alendronate is appropriate for you.

Availability of alendronate in the UK with NHS prescription

Alendronate is available with a National Health Service (NHS) prescription in the United Kingdom. It can be obtained from pharmacies with a valid prescription from a healthcare professional.

Conditions treated by alendronate

Alendronate is primarily used for the treatment of postmenopausal osteoporosis, prevention of postmenopausal osteoporosis, steroid-induced osteoporosis, male osteoporosis, and Paget’s disease of bone. It helps to strengthen bones, reduce the risk of fractures, and improve bone density. Preexistent hypocalcemia (low calcium levels) must be corrected before initiating alendronate therapy. Similarly, vitamin D deficiency must also be corrected.

How does alendronate work?

Alendronate works by inhibiting the activity of cells called osteoclasts, which are responsible for breaking down bone tissue. By reducing bone resorption, alendronate helps to maintain or increase bone mineral density.

Forms of alendronate available

Alendronate is available in various dosage forms, including oral tablets and an effervescent tablet called Binosto, which is dissolved in water before consumption.

Dosage of alendronate

The dosage of alendronate may vary depending on individual factors such as age, sex, and bone density. It is typically taken once weekly or as prescribed by a healthcare provider. It is important to follow the dosage instructions provided and not exceed the prescribed dose. If you miss a dose, skip the missed dose. Take your next dose at the regular time the following day. Do not double the dose to catch up.

Directions for alendronate use

Alendronate tablets should be taken in the morning on an empty stomach, at least 30 minutes before the first food, beverage, or medication of the day. It should be swallowed whole with a full glass of water. Do not use coffee, tea, soda, mineral water or juice, only plain water. After you take alendronate, do not eat, drink, or take any other medications (including vitamins such as magnesium or calcium supplements or antacids) for at least 30 minutes as it can decrease the absorption of alendronate. Do not lie down for at least 30 minutes after you take alendronate. This will help alendronate reach your stomach faster. It will also help prevent irritation to your esophagus. Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.

Side effects of alendronate

Common side effects of alendronate may include gastrointestinal symptoms such as nausea, abdominal pain, constipation and heartburn. It may also cause musculoskeletal symptoms such as bone, joint, or muscle pain. In rare cases, alendronate may cause serious side effects, including osteonecrosis of the jaw and atypical fractures of the thigh bone. It is important to seek medical attention if you experience any severe or persistent side effects. A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of serious allergic reactions; hives, wheezing, difficulty breathing; swelling of your face, lips, tongue, or throat.

Precautions and warnings

Some of the precautions and warnings include:

  • Alendronate can cause irritation, inflammation, or ulcers in the esophagus (the tube that connects the mouth to the stomach). It is essential to take the medication with a full glass of plain water on an empty stomach and remain upright for at least 30 minutes afterwards to minimize the risk of these issues
  • Rare cases of osteonecrosis of the jaw (a serious condition where the jawbone does not heal after injury) have been reported in patients taking alendronate. You should inform your healthcare provider if you experience jaw pain, swelling, numbness, or difficulty healing after dental procedures
  • Some individuals may experience severe bone, joint, or muscle pain while taking alendronate. If you experience persistent or worsening pain, it is important to consult your healthcare provider
  • Adequate intake of calcium and vitamin D is crucial for maintaining bone health. Long-term use of alendronate may lead to deficiencies in these nutrients. Your healthcare provider may recommend calcium and vitamin D supplements to ensure adequate levels
  • Some people may experience allergic reactions to alendronate, such as rash, itching, swelling, dizziness, or trouble breathing. It is important to seek immediate medical attention if you experience any of these symptoms
  • Alendronate can cause serious side effects, such as severe bone, joint, or muscle pain, unusual fractures, and atrial fibrillation (a heart rhythm disorder). If you experience any of these symptoms, it is important to contact your healthcare provider right away

These warnings highlight the potential adverse events associated with use of alendronate. It is important to weigh the benefits and risks with your healthcare provider before starting or continuing this medication.

Drug interactions 

Alendronate may interact with certain medications, supplements, or foods. It is important to inform your healthcare provider about all medications and supplements you are taking to avoid potential adverse effects.

Is alendronate safe to take if I am pregnant or planning to become pregnant?

Alendronate is not recommended for use during pregnancy. It is important to discuss the potential risks and benefits of alendronate use if you are pregnant or planning to become pregnant.

Is alendronate safe to take if I am breastfeeding?

Alendronate is not recommended for use while breastfeeding. It is important to consult with a healthcare provider for individualized recommendations.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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