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Alendronate is available as a 5 mg, 10 mg, 35 mg, 40 mg and 70 mg oral tablet and a 70 mg/75 ml oral solution,

Alendronate is a bisphosphonate and can be used for the prevention and treatment of osteoporosis in females, the treatment of osteoporosis in males, and Paget’s disease.

Alendronate is a bisphosphonate. It attaches to bones to prevent bone breakdown, lowering the risk of fractures.

Alendronate is typically taken by mouth and dosed 35 mg or 75 mg once a week or 5 mg to 40 mg every day.

Alendronate is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have abnormalities of the esophagus which delay emptying such as stricture or achalasia.

Common side effects of Alendronate include:

• Stomach pain
• Muscle, bone, and joint pain
• Heartburn or indigestion
• Nausea
• Passing gas

Serious side effects are rare with Alendronate. Contact your healthcare provider immediately if you experience any of the following.

• Allergic reactions: trouble breathing, hives, swelling of your face, lips, tongue, or throat
• Low calcium levels

The following medications may interact with Alendronate:

• Calcium supplements, antacids, or oral medications containing multivalent cations interfere with absorption of Alendronate
• Aspirin and nonsteroidal anti-inflammatory drug use may worsen GI irritation therefore use with caution

Various FDA-approved generic manufacturers

Alendronate use has not been studied in pregnant women. Alendronate should be used during pregnancy only if the
potential benefit justifies the potential risk to the mother and fetus.

• Fosamax