Used for Cancer

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Updated on 24 Apr 2024

Learn more about alectinib

What dosages is alectinib available in?

What dosages is alectinib available in?

alectinib is available as a 150 mg oral capsule.

What is alectinib used for?

What is alectinib used for?

alectinib is a kinase inhibitor used to treat anaplastic lymphoma kinase (ALK)-positive metastatic non-small cell lung cancer (NSCLC).

How does alectinib work?

How does alectinib work?

alectinib is a targeted therapy anticancer medication. Specifically, it’s a tyrosine kinase inhibitor that blocks a protein called anaplastic lymphoma kinase (ALK).

  • The ALK protein is made by the ALK gene. This gene is something that everyone is born with. It plays an important role in helping babies develop in the womb. In people with ALK-positive NSCLC, this gene doesn’t work like it should. It ends up making abnormal proteins and causing cancer
  • By blocking the abnormal ALK protein, alectinib can help slow or stop the spread of NSCLC cells that are ALK-positive
How do I take alectinib?

How do I take alectinib?

The typical dose of alectinib is 600 mg by mouth twice daily with food. Your dose of alectinib might be lower if you have liver problems.

Is it safe for me to take alectinib?

Is it safe for me to take alectinib?

alectinib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.

alectinib Common Side Effects

alectinib Common Side Effects

Common side effects of alectinib:

  • Low red blood cell count
  • High liver lab values, such as bilirubin, AST, and ALT
  • Tiredness
  • High creatinine levels
  • High creatine phosphokinase
  • Constipation
  • Swelling in the hands and feet
  • Low blood calcium levels
  • Muscle aches and pain
  • High blood sugar
  • Cough
  • Low sodium levels
  • High or low potassium levels
  • Rash
alectinib Serious Side Effects

alectinib Serious Side Effects

Serious side effects are rare with alectinib. Contact your healthcare provider immediately if you experience any of the following.

  • Serious lungs problems: trouble breathing, cough, or fever
  • Dangerously slow heart beat: Tiredness, weakness, feeling dizzy or confused, feeling faint, trouble breathing, chest pain, getting tired easily during physical activity
  • Serious liver problems: feeling very tired, nausea, vomiting, itchy skin, yellowing of the whites of the eyes or skin, stomach pain and swelling, swelling in the legs or ankles, dark-colored urine, pale-colored stool
  • Kidney problems: feeling confused, tiredness, nausea, vomiting, change in urine color, change in amount of urine produced, or swelling in the legs and feet
Effects of other drugs, drug classes and over-the-counter products on alectinib

Effects of other drugs, drug classes and over-the-counter products on alectinib

  • There are no major drug interactions listed for alectinib. However, always let your physician and pharmacist know about any other medications or supplements (including prescribed and over-the-counter medications, vitamins, and dietary or herbal supplements) that you are currently taking
Who makes alectinib?

Who makes alectinib?

Various FDA-approved generic manufacturers

Is alectinib safe in pregnancy?

Is alectinib safe in pregnancy?

alectinib can harm your unborn baby. Tell your healthcare provider right away if you become pregnant during treatment with alectinib or think you may be pregnant.
Females who are able to become pregnant should use effective birth control during treatment with alectinib and for 1 week after the final dose of alectinib. Males who have female partners that are able to become pregnant should use effective birth control during treatment with alectinib and for 3 months after the final dose of alectinib.


What to do if you missed your alectinib dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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