AcyclovirPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  1. Medication
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  2. Acyclovir
    Generic for Zovirax
    30 tablets $5.7 USD
    Save $20.10
  3. Acyclovir
    Generic for Zovirax
    30 tablets $6.3 USD
    Save $19.50
  4. Acyclovir
    Generic for Zovirax
    30g (76) tube of ointments $14.63 USD
    Save $50.73
  5. Acyclovir
    Generic for Zovirax
    200mg/5mL 473mL
    473mL (482) bottle of suspensions $76.82 USD
    Save $337.70
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Do you need a prescription for acyclovir?

Yes, acyclovir is only available with a valid physician Rx.

How much is acyclovir without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase acyclovir, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for acyclovir in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a acyclovir savings card?

Yes. Save up to 90% on your acyclovir with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a acyclovir coupon provider in the US?

No. Now Patient does not provide acyclovir coupons or FREE acyclovir samples.

Do you accept commercial, Medicare or Medicaid coverage for acyclovir in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much acyclovir?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using acyclovir. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much acyclovir. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic acyclovir?

Generic acyclovir refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of acyclovir

Acyclovir is approved by the U.S. Food and Drug Administration (FDA) for the treatment of various viral infections, including herpes simplex virus (HSV) infections and varicella-zoster virus (VZV) infections.

Active ingredient of acyclovir

The active ingredient of acyclovir is acyclovir.

US brand name of acyclovir and manufacturer

Acyclovir is available in the US under various brand names, including Zovirax. It is manufactured by various pharmaceutical companies.

UK brand name of acyclovir and manufacturer

In the UK, acyclovir is called aciclovir and is available under various brand names, including Zovirax. The manufacturer may vary depending on the brand name.

Prescription requirement for acyclovir

A prescription (Rx) is required for acyclovir in both the US and the UK.

Availability of aciclovir in the UK with NHS prescription

Acyclovir is available in the UK with an NHS prescription.

Conditions treated by acyclovir

Acyclovir belongs to a class of antiviral drugs called synthetic nucleoside analogues. It is used for the treatment of viral infections caused by herpes simplex virus (HSV), including outbreaks of genital herpes, chickenpox, cold sores, and shingles (herpes zoster). It may also be used for the prevention of recurrent herpes outbreaks. This medication works best when started at the first sign of an outbreak, as directed by your doctor.

How does acyclovir work?

Acyclovir works by inhibiting the replication of the herpes virus. It blocks the action of an enzyme called DNA polymerase, which is essential for the replication of the viral DNA. By preventing the virus from replicating, acyclovir helps reduce the severity and duration of herpes outbreaks by reducing pain and speeding the healing of sores or blisters.

Forms of acyclovir available

Acyclovir is available in various forms, including oral tablets, capsules, topical creams, and intravenous (IV) formulations.

Dosage of acyclovir

The dosage of acyclovir may vary depending on the specific condition being treated, the patient’s age and weight, and other individual factors. It is important to follow the prescribed dosage instructions provided by the healthcare provider. Take a missed dose as soon as you can. If it is almost time for your next dose, take only that dose. Do not take double or extra doses.

Directions for acyclovir use

Acyclovir should be taken exactly as directed by the healthcare provider. The medication is usually taken orally with or without food. For topical creams, apply a thin layer to the affected area as directed. For IV formulations, it is administered by a healthcare professional. Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light.

Warnings and precautions for acyclovir

  • Acyclovir should be used with caution in individuals with certain medical conditions, such as kidney disease or compromised immune systems. Dose adjustments may be necessary
  • Get emergency medical help if you have signs of an allergic reaction to acyclovir: hives; difficulty breathing; swelling of your face, lips, tongue, or throat
  • Drug interactions with certain medications, including probenecid and nephrotoxic drugs. Inform the healthcare provider about all medications being taken
  • Use with caution in immunocompromised patients

Drug interactions

Acyclovir may interact with certain medications, including prescription drugs, over-the-counter medications and herbal supplements. It is important to inform your healthcare provider about all the medications you are taking to avoid potential drug interactions and adverse effects.

Use of acyclovir during pregnancy

The use of acyclovir during pregnancy should be carefully considered, and the potential risks and benefits should be discussed with a healthcare provider.

Use of acyclovir while breastfeeding

Acyclovir is excreted in breast milk but is generally considered safe to use while breastfeeding. It is recommended to consult a healthcare provider for medical advice before using acyclovir while breastfeeding.

Possible side effects of acyclovir

Common side effects of acyclovir may include nausea, vomiting, diarrhea, and headache. Serious side effects are rare but can occur. Promptly report any concerning symptoms to a healthcare provider.

Similar drugs to acyclovir

Other antiviral medications used for the treatment of herpes infections include valacyclovir and famciclovir.



Now Patient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information in this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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