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mirtazapine

mirtazapine

Used for Depression

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Manufactured by various FDA-approved generic manufacturers.

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Updated on 24 Apr 2024

mirtazapine Uses, Side Effects, Interactions, Warnings & Dosing

What dosages is mirtazapine available in?

What dosages is mirtazapine available in?

mirtazapine is available as a 15 mg, 30 mg, and 45 mg orally disintegrating tablet.

What is mirtazapine used for?

What is mirtazapine used for?

mirtazapine is an atypical antidepressant that is used to treat depression in adults.

How does mirtazapine work?

How does mirtazapine work?

mirtazapine is an antidepressant. It works by raising the levels of serotonin and norepinephrine in your brain, which are important chemicals involved with regulating your mood.

How do I take mirtazapine?

How do I take mirtazapine?

mirtazapine is typically started at 15 mg by mouth (or dissolved under the tongue for ODT) once daily, typically in the evening. Your provider might raise your dose every 1 to 2 weeks, depending on how well this medication works for you. The maximum recommended dose is 45 mg once daily.

Is it safe for me to take mirtazapine?

Is it safe for me to take mirtazapine?

mirtazapine is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you. You should not use this medication if you have taken an MAOI within the past 14 days.

mirtazapine Common Side Effects

mirtazapine Common Side Effects

Common side effects of mirtazapine:

  • Sleepiness
  • Dry mouth
  • Feeling more hungry
  • Constipation
  • Weight gain
  • Weakness
  • Dizziness
mirtazapine Serious Side Effects

mirtazapine Serious Side Effects

Serious side effects are rare with mirtazapine. Contact your healthcare provider immediately if you experience any of the following.

  • Suicidal thoughts or behaviors
  • Serotonin syndrome: fast heart rate, dizziness, sweating, flushing, tremor (shakiness), muscle stiffness, muscle twitching or spasms, uncoordinated movement, distress, seizures, hallucinations, coma
  • Abnormal heart rhythm (QT prolongation): chest pounding, short of breath, chest pain, feeling faint or lightheaded
  • Seizures
  • Serious allergic and skin reactions: hives, rash, blisters, swelling of the lips or tongue, difficulty breathing, skin reddening, blisters, rash
  • Low blood sodium levels: nausea, fatigue, headache, confusion, disoriented, hallucinations (seeing things that aren’t real), seizures, unconsciousness
Effects of other drugs, drug classes and over-the-counter products on mirtazapine

Effects of other drugs, drug classes and over-the-counter products on mirtazapine

The following medications may interact with mirtazapine:

  • Strong CYP3A inducers: Dosage increase may be needed for mirtazapine with concomitant use of strong CYP3A inducers
  • Strong CYP3A inhibitors: Dosage decrease may be needed when mirtazapine is coadministered with strong CYP3A inhibitors
  • Cimetidine: Dosage decrease may be needed when mirtazapine is coadministered with cimetidine
  • Warfarin: Monitor INR during concomitant use
Who makes mirtazapine?

Who makes mirtazapine?

Various FDA-approved generic manufacturers

Is mirtazapine safe in pregnancy?

Is mirtazapine safe in pregnancy?

It is not known if mirtazapine will harm your unborn baby. You should talk to your healthcare provider before taking this medication if you are pregnant. There is a pregnancy exposure registry that monitors pregnancy outcomes in women exposed to antidepressants during pregnancy. Healthcare providers are encouraged to register patients by calling the
National Pregnancy Registry for Antidepressants at 1-844-405-6185 or visiting online at women’s health

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What to do if you missed your mirtazapine dose

The FDA's medical product safety reporting program for health professionals, patients and consumers.

Learn more about reporting side effects
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Medical Disclaimer

NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.

The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.

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