glasdegib
Used for Cancer
Are you tired of high medication costs? Our service offers unbeatable savings on your glasdegib prescription medication. We provide a range of solutions to help you save up to 100% on your medication costs*. Whether you are insured, uninsured, underinsured, or simply looking to reduce your out-of-pocket expenses, we've got you covered.
Manufactured by various FDA-approved generic manufacturers.
*You can pay as little as $0 per fill using Drug Coupons or Patient Assistance Programs. Subject to applicability & eligibility requirements.
This content is intended for US audiences only
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glasdegib key facts
What dosages is glasdegib available in?
glasdegib is available as a 25 mg and 100 mg oral tablet.
What is glasdegib used for?
glasdegib is a hedgehog pathway inhibitor and is used for the following:
- Newly-diagnosed acute myeloid leukemia (AML), given with low-dose cytarabine (Ara-C) chemotherapy, in:
- Adults who are 75 years of age or older
- Adults who have other health problems that prevent them from receiving intensive chemotherapy
How does glasdegib work?
glasdegib is a Hedgehog pathway inhibitor. By blocking the Hedgehog pathway, the medication slows cancer growth. Blocking the pathway also helps prevent drug resistance and allows other leukemia medications like cytarabine (Ara-C) to work better. When glasdegib is used with cytarabine, the two medications work together to fight the cancer.
How do I take glasdegib?
glasdegib is typically dosed at 100 mg by mouth once a day. glasdegib is taken every day during each 28-day treatment cycle. glasdegib is taken together with a low dose of a chemotherapy medication called cytarabine, which is given as an injection on days 1 to 10 of the 28-day treatment cycle.00 mg by mouth once a day. glasdegib is taken every day during each 28-day treatment cycle. glasdegibis taken together with a low dose of a chemotherapy medication called cytarabine, which is given as an injection on days 1 to 10 of the 28-day treatment cycle.
Is it safe for me to take glasdegib?
glasdegib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
glasdegib Common Side Effects
Common side effects of glasdegib:
- Higher blood creatinine levels
- Changes in electrolyte levels in blood
- Anemia
- Bleeding
- Tiredness
- Neutropenic fever
- Low platelet count
- Swelling
- Muscle, joint, or bone pain
- Nausea
- Higher liver enzyme levels in blood cell count
- Trouble breathing
- Lower appetite
- Taste changes
- Mouth sores
- Rash
- Constipation
glasdegib Serious Side Effects
Serious side effects are rare with glasdegib. Contact your healthcare provider immediately if you experience any of the following.
- Changes in heart rhythm: lightheadedness, irregular heartbeat, blurry vision, fainting, loss of consciousness, seizures
Effects of other drugs, drug classes and over-the-counter products on glasdegib
The following medications may interact with glasdegib:
- Strong CYP3A4 Inhibitors: Consider alternative therapies that are not strong CYP3A4 inhibitors or monitor for increased risk of adverse reactions, including QTc interval prolongation
- Strong CYP3A4 Inducers: Avoid concomitant use with glasdegib
- Moderate CYP3A4 Inducers: Avoid concomitant use with glasdegib. If, concomitant use cannot be avoided, increase the dose of glasdegib
- QTc Prolonging Drugs: Avoid co-administration with glasdegib. If co-administration is unavoidable, monitor for increased risk of QTc interval prolongation
Who makes glasdegib?
Various FDA-approved generic manufacturers
Is glasdegib safe in pregnancy?
glasdegib can cause fetal harm when administered to a pregnant woman. Conduct pregnancy testing in females of reproductive potential within 7 days prior to initiating therapy with glasdegib. Advise females of reproductive potential to use effective contraception during treatment with glasdegib and at least 30 days after the last dose. Males should use effective contraception, including a condom, even after a vasectomy, to avoid drug exposure to a pregnant partner or a female partner of reproductive potential during treatment with glasdegib and for at least 30 days after the last dose. Advise males to not donate semen during treatment with glasdegib for at least 30 days after the last dose.
The FDA's medical product safety reporting program for health professionals, patients and consumers.
Learn more about reporting side effectsDrug Savings Guide
A practical guide to saving money and receiving support with prescription costs
How can NowPatient help me to lower the cost of my glasdegib prescription?
After you create a FREE account with NowPatient, you will have access to 4 programs that can help lower the cost of your glasdegib prescription
Applicability to each program will be dependent on your insurance status.
How do the NowPatient glasdegib savings programs work?
After you have created your FREE account with NowPatient, you can access the various programs from your account dashboard. Each program has clear instructions on how to check your eligibility. You can see how the process works by clicking on the feature link below and seeing the ‘How it works’ steps.
Drug Coupon and Patient Assistance Programs require an eligibility quiz to be completed.
Are the NowPatient glasdegib savings programs suitable for everyone, regardless of insurance status?
No. Each program has its own eligibility and applicability requirements. The table below shows if a program is available to you, based on your insurance status.
| Rx Advantage Card* for glasdegib | Canadian Prescription Savings* for glasdegib | glasdegib Drug Coupon* | glasdegib Patient Assistance Program* | |
| Insured (federal, state or government) | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured (Commercial or Private) | Available | Available | Available If Offered by Pharmaceutical Company | Available If Offered by Pharmaceutical Company |
| Uninsured | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
| Insured but without pharmacy benefit or drug coverage | Available | Available | Not Available | Available If Offered by Pharmaceutical Company |
*This is not insurance.
Are the NowPatient drug savings programs suitable for brand and generic versions of glasdegib?
No. Each program has applicability requirements. Please see below
| Rx Advantage Card* for glasdegib | Canadian Prescription Savings* for glasdegib | glasdegib Drug Coupon* | glasdegib Patient Assistance Program* | |
| Brand | Yes | Yes | Yes, If Offered by Pharmaceutical Company | Yes, If Offered by Pharmaceutical Company |
| Generic | Yes | Yes | No | No |
*This is not insurance.
If you have Medicare Part D or Medicare Advantage and none of the glasdegib savings options are applicable or affordable for me, what can you do?
If you are insured with Medicare and the glasdegib drug savings options are not applicable to you and still remain unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and after you have selected your state, it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
People who qualify for both Medicare and Medicaid are called ‘dual eligibles’.
If you are denied Medicaid for glasdegib, and you are still unable to afford your copay or co-insurance element (for example if you are in the coverage gap or Donut Hole) then you may be eligible for a federal support program like Low Income Subsidy. To be eligible for Low Income Subsidy, you need to be a resident in one of the 50 States or the District of Columbia. You can check eligibility online at SSA Medicare D Extra Help. You can also call Social Security at 1-800-772-1213 (TTY 1-800-325-0778).
I am uninsured or underinsured and none of the glasdegib prescription saving options are applicable or affordable for me, what can I do?
If you are uninsured or underinsured (for example, glasdegib is not covered by your plan) and the drug savings options are not applicable or still unaffordable, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. State Medicaid programs may cover the full cost of your medication.
If you are denied and all else fails, and if you have been prescribed glasdegib for an FDA-approved indication, you can call the pharmaceutical company to see if they have any other assistance programs.
I am commercially or privately insured and none of the glasdegib prescription saving options are applicable or affordable for me, what can I do?
If your medication is not covered by your plan, you can appeal your insurance company’s decision. Sometimes, a formal appeal can result in the drug being covered if it is deemed medically necessary.
If you cannot afford your copay contribution, then you can check Medicaid eligibility in your state by following the instructions at HealthCare.gov.
However, being privately insured might complicate your eligibility for Medicaid, as having private insurance may be considered in the financial eligibility assessment.
The government site is easy to use and you can select your state and it will navigate you to the appropriate contact point to make the application. If you qualify, state Medicaid may cover the full cost of your medication.
If I have federal, state or commercial insurance and none of the glasdegib prescription saving options are applicable or affordable for me, are there any other support organisations that can help me with my co-insurance or copay contributions?
If you have already tried Medicaid and received a denial letter or if you are insured with Medicare and have been denied Low-Income Subsidy, then you can try one of the following organizational support programs:
1. Patient Access Network Foundation (PAN) assistance for glasdegib
If you are having trouble paying for your glasdegib medication due to unaffordable copays or deductibles, the Patient Access Network Foundation (PAN), may be able to assist you. To qualify for PAN assistance for glasdegib you will need to meet one or all of the following criteria:
- Your income is below 400% of the federal poverty level
- glasdegib is prescribed for an approved FDA indication
- You live in and receive treatment in the United States or U.S. territories, even if you do not have U.S. citizenship
- You have Medicare insurance coverage that covers glasdegib
- If glasdegib is listed on PAN’s list of covered medications
You can check the Patient Access Network Foundation Website for more information.
2. HealthWell Foundation Copay Program for glasdegib
If you are having trouble paying for your glasdegib medication due to unaffordable copays or deductibles, the HealthWell Foundation Copay Program may be able to assist you. To qualify for assistance for glasdegib you will need to meet the following criteria:
- You live in and are being treated in the United States
- You are insured and your plan covers glasdegib
- If glasdegib is listed on the HealthWell Foundation’s list of covered medications
You can check the HealthWell Foundation Website for more information.
3. Patient Advocate Foundation Co-Pay Relief Program for glasdegib
Patient Advocate Foundation’s Co-Pay Relief program exists to help reduce the financial distress you or your family may face when paying for your glasdegib treatment. If you qualify and can demonstrate the need, the foundation will provide you with direct payment covering co-pays, co-insurance, and deductibles. To qualify for assistance for glasdegib you will need to meet the following criteria:
- You must be currently insured and have coverage for glasdegib
- You must have a confirmed diagnosis and treatment plan
- You must reside and receive treatment in the United States
- Your Income must fall at or below 300% or 400% of the Federal Poverty Guideline (FPG) with consideration for the Cost of Living Index (COLI) and number in the household
- Applications can also be completed by contacting the program sponsor, toll-free at 866-512-3861.
You can check the Patient Advocate Foundation Website for more information.
Medical Disclaimer
NowPatient has taken all reasonable steps to ensure that all material is factually accurate, complete, and current. However, the knowledge and experience of a qualified healthcare professional should always be sought after instead of using the information on this page. Before taking any drug, you should always speak to your doctor or another qualified healthcare provider.
The information provided here about medications is subject to change and is not meant to include all uses, precautions, warnings, directions, drug interactions, allergic reactions, or negative effects. The absence of warnings or other information for a particular medication does not imply that the medication or medication combination is appropriate for all patients or for all possible purposes.
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You can lower the cost of your prescription medications using our various savings programs which include drug coupons, savings card and manufacturer-sponsored patient assistance programs.
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