Key facts about Copanlisib
What dosages is Copanlisib available in?
Copanlisib is available as an IV infusion that contains 60 mg of Copanlisib.
What is Copanlisib used for?
Copanlisib is a kinase inhibitor that is used to treat adult patients
with relapsed follicular lymphoma (FL) who have received at least two prior systemic therapies.
How does Copanlisib work?
Copanlisib works by blocking a protein that causes cancer cells to grow and multiply. This helps to slow or stop the spread of cancer cells.
How do I take Copanlisib?
Copanlisib will be given to you by your healthcare provider via a 1-hr infusion. Your dose may be decreased if you have bad side effects or liver problems.
Is it safe for me to take Copanlisib?
Copanlisib is a safe and effective treatment when used for FDA licensed indications. However, like all medications, they may give you unwanted side effects. You should always discuss potential side effects with your physician to ensure the medication is suitable and right for you.
Copanlisib Common Side Effects
Common side effects of Copanlisib:
- Diarrhea
- Low platelet counts (thrombocytopenia)
- Decreased strength and tiredness
- Lower respiratory tract infection
- Nausea
Copanlisib Serious Side Effects
Serious side effects are rare with Copanlisib. Contact your healthcare provider immediately if you experience any of the following.
- Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
- Dry cough, shortness of breath or trouble breathing.
High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness or fatigue, blurry vision - Increase in blood pressure
- Infection—fever, chills, cough, sore throat, wounds that don’t heal, pain or trouble when passing urine, general feeling of discomfort or being unwell
- Redness, blistering, peeling, or loosening of the skin, including inside the mouth
- Unusual bruising or bleeding
Effects of other drugs, drug classes and over-the-counter products on Copanlisib
The following medications may interact with Copanlisib:
- CYP3A Inducers: Avoid concomitant use with strong CYP3A inducers
- CYP3A Inhibitors: Reduce the Copanlisib dose to 45 mg when concomitantly administered with strong CYP3A inhibitors
Who makes Copanlisib?
Various FDA-approved generic manufacturers
Is Copanlisib safe in pregnancy?
Copanlisib can harm your unborn baby. Your healthcare provider will do a pregnancy test before starting treatment with Copanlisib. Females who are able to become pregnant should use effective birth control (contraception) during treatment with Copanlisib and for 1 month after the last dose of Copanlisib. Talk to your healthcare provider about birth control methods that may be right for you. Tell your healthcare provider right away if you become pregnant or think you are pregnant during treatment with Copanlisib.
Males with female partners who are able to become pregnant should use effective birth control (contraception) during treatment with Copanlisib and for 1 month after the last dose of Copanlisib.
