Buy Elleste Duet online with free consultation & prescription
Book a quick face-to-face video consultation with a UK certified prescribing pharmacist, nurse, or doctor. If approved, your Elleste Duet will be prescribed* and delivered straight to your door within 10-14 working days. Avoid doctor waiting lists. No delays. Just expert care.
Elleste Duet is indicated for the treatment of Menopause.
*Includes Free Private Prescription & Consultation.
Manufactured by Mylan.

Elleste Duet doses and pack sizes

Elleste Duet
Elleste Duet doses and pack sizes
*Your clinician will recommend the right strength and quantity for you during the consultation.
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Elleste Duet prices
| Brand/Generic | Form | Dosage | Quantity | Price | Delivery Cost | Consultation Cost |
|---|---|---|---|---|---|---|
| Elleste DuetBrand | Tablets | 1mg | 84 | £46.34 | £0.00*(with Core+ Plan) | £0.00 |
| Elleste DuetBrand | Tablets | 2mg | 84 | £47.84 | £0.00*(with Core+ Plan) | £0.00 |
FAQs
Answers to popular questions about Elleste Duet
What is Elleste Duet?
Elleste Duet is a combined sequential HRT product containing oestradiol and norethisterone acetate. It is available as Elleste Duet 1 mg (1 mg oestradiol + 1 mg norethisterone) and Elleste Duet 2 mg (2 mg oestradiol + 1 mg norethisterone). The pack contains 16 white oestrogen-only tablets followed by 12 green combined (oestrogen + progestogen) tablets. It is used for menopausal symptom relief in women with an intact uterus who are perimenopausal or within 12 months of their last period.
How does Elleste Duet work?
Elleste Duet provides oestradiol continuously to relieve menopausal symptoms, with norethisterone added for 12 days each cycle to protect the womb lining (endometrium) from the thickening effect of unopposed oestrogen. This sequential pattern produces a predictable monthly withdrawal bleed, similar to a period, during or after the progestogen phase. This is the standard approach for women who are still having some periods (perimenopausal) or have been menopausal for less than 12 months.
What is the difference between Elleste Duet and Elleste Solo?
Elleste Solo contains oestradiol only and is intended for women who have had a hysterectomy. Elleste Duet combines oestradiol with norethisterone (a progestogen) and is intended for women with an intact uterus, as the progestogen protects the womb lining. If you still have your womb, you need a combined HRT product or must add a separate progestogen to oestrogen-only HRT.
How do I take Elleste Duet?
Take one tablet daily at the same time. Start with the 16 white (oestrogen-only) tablets, then take the 12 green (oestrogen + progestogen) tablets. After finishing the 28-tablet pack, start a new pack immediately without a break. A withdrawal bleed usually occurs during or just after the green tablet phase. Take the tablets in the correct order as marked on the pack.
When should I switch to continuous combined HRT?
Sequential HRT (like Elleste Duet) produces a monthly withdrawal bleed. Once you have been postmenopausal for at least 12 months, your prescriber may recommend switching to a continuous combined HRT (such as Kliofem or Kliovance), which aims to be bleed-free. Switching too early may cause irregular breakthrough bleeding. Your prescriber will advise on the optimal timing.
What are the side effects of Elleste Duet?
Common side effects include breast tenderness, headaches, nausea, bloating, and mood changes. The progestogen phase (green tablets) may cause PMS-like symptoms including mood changes, bloating, and breast tenderness. Breakthrough bleeding outside the expected withdrawal bleed may occur in the first 3 months. Leg cramps and skin reactions are uncommon.
What are the risks of Elleste Duet?
Combined HRT (oestrogen + progestogen) is associated with a small increased risk of breast cancer with use beyond 5 years. The risk increases with duration and returns to baseline within a few years of stopping. Oral HRT carries a small increased VTE risk. Transdermal oestrogen with micronised progesterone (Utrogestan) may offer a lower-risk profile. Your prescriber will discuss your individual risk-benefit balance.
Is Elleste Duet body-identical HRT?
Elleste Duet contains body-identical oestradiol (17β-estradiol, identical to the oestrogen produced by the ovary), but the progestogen component (norethisterone acetate) is a synthetic progestogen, not body-identical progesterone. For a fully body-identical regimen, some prescribers recommend oestradiol (tablets, patches, or gel) combined with micronised progesterone (Utrogestan). Discuss your preferences with your prescriber.
How can I get Elleste Duet?
You can request Elleste Duet through NowPatient by completing a short online consultation with one of our prescribing clinicians. Your clinician will review your menopausal symptoms, medical history and risk factors such as blood clots and breast cancer to decide whether Elleste Duet is the right HRT for you. If treatment is suitable, a prescription is issued and your medication is dispensed by our registered pharmacy and delivered to your door.
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