Buy Estriol online with free consultation & prescription

Book a quick face-to-face video consultation with a UK certified prescribing pharmacist, nurse, or doctor. If approved, your Estriol will be prescribed* and delivered straight to your door within 10-14 working days. Avoid doctor waiting lists. No delays. Just expert care.

Estriol is indicated for the treatment of Menopause.

*Includes Free Private Prescription & Consultation.

Manufactured by Marlborough Pharma.

Estriol packaging which is available to order online from NowPatient with free next day delivery
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Estriol packaging which is available to order online from NowPatient with free next day delivery

Estriol

Estriol doses and pack sizes

*Your clinician will recommend the right strength and quantity for you during the consultation.

Treatment£82.35
Shipping£25.00
Total if approved£107.35

How it works

Fast, simple booking with a certified prescribing clinician

If approved, get your treatment prescription

Get tracked delivery straight to your door

No hidden fees. No delays.

Similar treatments

Estriol alternatives

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Estriol prices

Brand/GenericFormDosageQuantityPriceDelivery CostConsultation Cost
EstriolBrandCream0.01%80 grams£82.35£0.00*(with Core+ Plan)£0.00

FAQs

Answers to popular questions about Estriol

What is Estriol?

Estriol (oestriol) is a weak, naturally occurring oestrogen used topically to treat vulvovaginal atrophy (also called genitourinary syndrome of menopause, GSM). It is available as a vaginal cream (e.g., Ovestin, Blissel) and pessaries. Estriol acts locally on the vaginal and urethral tissues and has minimal systemic absorption, making it very safe for long-term use. It does not require the addition of a progestogen even in women with an intact uterus when used vaginally at recommended doses.

How does Estriol work?

Estriol restores oestrogen to the vaginal and urethral tissues, reversing the thinning, dryness, and fragility caused by declining oestrogen levels after menopause. It increases vaginal lubrication, restores normal vaginal pH (reducing infections), strengthens the vaginal epithelium, and can improve urinary symptoms such as urgency and recurrent UTIs. Because systemic absorption is minimal at topical doses, it does not carry the risks associated with systemic HRT.

How do I use Estriol vaginal cream?

Insert one application of cream (0.5 g containing 0.5 mg estriol) into the vagina at bedtime using the applicator provided. Use daily for the first 2–3 weeks (initial treatment phase), then reduce to twice weekly for maintenance. Wash the applicator after each use. You may also apply a small amount externally to the vulva if needed. Always follow your prescriber’s specific instructions.

How long does Estriol take to work?

Most women notice improvement in vaginal dryness, itching, and discomfort within 2–3 weeks of starting estriol. Full benefit, including improvement in urinary symptoms and recurrent UTIs, may take 4–12 weeks. Estriol is intended for long-term use — symptoms will return if treatment is stopped.

What are the side effects of Estriol?

Side effects are uncommon because systemic absorption is minimal. Local irritation, burning, or itching may occur when first starting treatment, usually settling within a few days. Vaginal spotting may occur initially. Breast tenderness and headache are rare with topical estriol. Long-term vaginal estriol use is not associated with increased breast cancer or cardiovascular risk.

Do I need progestogen with vaginal Estriol?

No, vaginal estriol at standard doses does not require the addition of a progestogen, even in women with an intact uterus. menopause guidance confirm that the systemic absorption is too low to stimulate the endometrium. This makes it a very safe option for long-term management of vaginal atrophy.

Can I use Estriol alongside systemic HRT?

Yes, vaginal estriol can be used alongside systemic HRT (tablets, patches, gels) if systemic HRT alone does not adequately relieve vaginal symptoms. Many women need local vaginal oestrogen in addition to their systemic HRT.

How can I get Estriol?

You can request Estriol through NowPatient by completing a short online consultation with one of our prescribing clinicians. Your clinician will review your vaginal and urinary symptoms and your medical history, including any history of breast cancer, to check that Estriol is suitable for you. If treatment is suitable, a prescription is issued and your medication is dispensed by our registered pharmacy and delivered to your door.

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We are a broad skilled and passionate group of clinicians with experience of operating in regulated health systems in the United Kingdom & United States. Providing excellent care and advice is at the heart of everything we do.