Buy Sayana Press online with free consultation & prescription
Book a quick face-to-face video consultation with a UK certified prescribing pharmacist, nurse, or doctor. If approved, your Sayana Press will be prescribed* and delivered straight to your door within 10-14 working days. Avoid doctor waiting lists. No delays. Just expert care.
Sayana Press is a contraceptive pill alternative used for contraception.
*Includes Free Private Prescription & Consultation.
Manufactured by Pfizer Ltd.
Sayana Press doses and pack sizes
Sayana Press
Sayana Press doses and pack sizes
*Your clinician will recommend the right strength and quantity for you during the consultation.
Treatment£17.99
Shipping£25.00
Total if approved£42.99
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Sayana Press prices
| Brand/Generic | Form | Dosage | Quantity | Price | Delivery Cost | Consultation Cost |
|---|---|---|---|---|---|---|
| Sayana PressBrand | Prefilled Pen | 104mg/0.65ml | 1 | £17.99 | £0.00*(with Core+ Plan) | £0.00 |
FAQs
Answers to popular questions about Sayana Press
What is Sayana Press?
Sayana Press is a progestogen-only contraceptive injection containing medroxyprogesterone acetate 104 mg/0.65 ml in a pre-filled subcutaneous injection device. It provides contraceptive protection for 13 weeks (approximately 3 months). Unlike the older Depo-Provera injection (which is given intramuscularly by a healthcare professional), Sayana Press is designed for subcutaneous self-injection at home, making it more convenient. It is manufactured by Pfizer and is a prescription-only medicine.
How does Sayana Press work?
Sayana Press works primarily by suppressing ovulation through inhibition of the hypothalamic-pituitary-ovarian axis. Medroxyprogesterone acetate also thickens cervical mucus, making it difficult for sperm to reach the egg, and thins the endometrial lining, reducing the likelihood of implantation. These combined mechanisms make it a highly effective contraceptive method with over 99% effectiveness when injections are given on time.
Can I inject Sayana Press myself at home?
Yes, Sayana Press is specifically designed for self-administration at home. After initial training from a nurse or healthcare professional, you can inject it yourself subcutaneously (under the skin) into the front of the thigh or the abdomen. This removes the need for clinic appointments every 13 weeks. Your prescriber will arrange initial training and then can provide ongoing prescriptions. NowPatient can facilitate prescriptions for those trained in self-injection.
How do I inject Sayana Press?
Shake the pre-filled device firmly for 30 seconds before use. Clean the injection site (front of thigh or abdomen) with an alcohol swab. Pinch a large area of skin, insert the needle at a 45-degree angle, and slowly push the plunger down over 5–7 seconds until the device clicks and all the medication is delivered. Hold for 5 seconds, then withdraw. Press the skin firmly for a few seconds — do not rub. Dispose of the used device safely in a sharps bin.
When should I have my Sayana Press injection?
The first injection should be given within the first 5 days of your menstrual cycle for immediate protection. If started later, use condoms for the first 7 days. Subsequent injections are given every 13 weeks (91 days). You can have the injection up to 5 days early or up to 14 days late without needing additional contraception. If more than 14 days late, you may no longer be protected — use condoms and seek advice from your prescriber.
What are the side effects of Sayana Press?
Common side effects include irregular bleeding or spotting (especially in the first few months), weight gain (average 1.5–3 kg over 2 years), headache, mood changes, acne, breast tenderness, and reduced libido. Many women find that their periods become lighter and some stop altogether (amenorrhoea) after the first few injections. Injection site reactions (pain, induration, redness) may occur. A rare but important consideration is reduced bone mineral density with long-term use — discussed further below.
Does Sayana Press affect my bones?
Long-term use of medroxyprogesterone acetate (Sayana Press/Depo-Provera) is associated with a small reduction in bone mineral density (BMD). This is generally reversible after stopping the injection. contraception guidance advises that the benefits usually outweigh the risks for most women, but careful assessment is needed for women under 18 (whose bones are still developing) and those with risk factors for osteoporosis. A review should occur every 2 years for women using it long-term. Alternative contraception may be preferable for those at high osteoporosis risk.
How long does it take for fertility to return after stopping Sayana Press?
Fertility may take longer to return after stopping Sayana Press compared to other contraceptive methods. On average, it takes about 5–6 months after the last injection was due for periods and ovulation to resume, but it can take up to 12–18 months for some women. This is important to consider when planning pregnancy. It does not cause permanent infertility. If planning a pregnancy, discuss timing with your prescriber.
How can I get Sayana Press?
You can request Sayana Press through NowPatient by completing a short online consultation with one of our prescribing clinicians. Your clinician will review your medical history to check that Sayana Press is suitable for you. Before you inject at home for the first time, you will need training on self-injection from a healthcare professional; after that, ongoing prescriptions can be issued through NowPatient. If treatment is suitable, a prescription is issued and your medication is dispensed by our registered pharmacy and delivered to your door.
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