Buy Melatonin online with free consultation & prescription
Book a quick face-to-face video consultation with a UK certified prescribing pharmacist, nurse, or doctor. If approved, your Melatonin will be prescribed* and delivered straight to your door within 10-14 working days. Avoid doctor waiting lists. No delays. Just expert care.
Melatonin is indicated for the treatment of Jet Lag.
*Includes Free Private Prescription & Consultation.
Manufactured by Colonis.
Melatonin doses and pack sizes
Melatonin
Melatonin doses and pack sizes
*Your clinician will recommend the right strength and quantity for you during the consultation.
Treatment£44.84
Shipping£25.00
Total if approved£69.84
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Melatonin prices
| Brand/Generic | Form | Dosage | Quantity | Price | Delivery Cost | Consultation Cost |
|---|---|---|---|---|---|---|
| MelatoninGeneric | Tablets | 3mg | 30 | £44.84 | £0.00*(with Core+ Plan) | £0.00 |
FAQs
Answers to popular questions about Melatonin
What is Melatonin?
Melatonin is a hormone naturally produced by the pineal gland in the brain that helps regulate the body’s sleep–wake cycle (circadian rhythm). In the UK, melatonin is classified as a prescription-only medicine and is available in both immediate-release and prolonged-release formulations. The branded prolonged-release version, Circadin, contains 2 mg of melatonin and is licensed for short-term treatment of primary insomnia in adults aged 55 and over. Melatonin is also prescribed off-label for other sleep disorders, jet lag, and sleep difficulties in children with neurodevelopmental conditions.
What is Melatonin used for?
Melatonin is primarily used for the short-term treatment of insomnia, particularly in adults aged 55 and over where the quality of sleep is poor. It is also used off-label for jet lag, delayed sleep–wake phase disorder, shift work sleep disorder, and sleep disturbance in children with ADHD, autism spectrum disorder, or other neurodevelopmental conditions. NICE has issued guidance supporting the use of melatonin in children and young people with sleep problems when sleep hygiene measures have been insufficient.
How does Melatonin work?
Melatonin works by mimicking the action of naturally produced melatonin in the body. Melatonin levels normally rise in the evening in response to darkness, signalling to the brain that it is time to sleep. By supplementing with exogenous melatonin, the sleep–wake cycle can be reset or reinforced. Prolonged-release formulations like Circadin release melatonin gradually throughout the night, mimicking the natural secretion pattern. This helps reduce sleep onset latency (time to fall asleep), improve sleep quality, and increase total sleep time without the dependency risk associated with benzodiazepines or Z-drugs.
What is the usual dose of Melatonin?
For adults aged 55 and over with primary insomnia, the licensed dose is Circadin 2 mg, one tablet daily taken 1–2 hours before bedtime and after food, for up to 13 weeks. For jet lag, doses of 0.5 mg to 5 mg are commonly used for 2–5 days. For children with neurodevelopmental conditions, doses typically start at 1–2 mg and may be gradually increased up to 6 mg, as guided by a specialist. Always follow your prescriber’s specific dosing instructions as melatonin dosing varies considerably depending on the indication.
When should I take Melatonin?
Take melatonin 1–2 hours before your intended bedtime. Prolonged-release tablets (Circadin) should be taken after food and swallowed whole — do not crush or chew them, as this destroys the prolonged-release mechanism. For jet lag prevention, take melatonin at the local bedtime at your destination on the day of arrival and for 2–5 subsequent evenings. Taking melatonin at the correct time relative to your intended sleep time is crucial for its effectiveness.
What happens if I take too much Melatonin?
Melatonin is generally considered safe even at higher-than-recommended doses, but taking too much can cause excessive drowsiness, headache, dizziness, nausea, and confusion. Very high doses may paradoxically disrupt sleep patterns. If you accidentally take an extra dose, you are unlikely to experience serious harm, but you may feel excessively drowsy the following day. Do not drive or operate machinery if you feel drowsy. If you are concerned about an overdose, contact your local poison control centre for advice.
What are the common side effects of Melatonin?
Common side effects of melatonin (affecting 1 in 10 to 1 in 100 people) include headache, drowsiness the next day, dizziness, and nausea. Uncommon side effects include dry mouth, vivid dreams or nightmares, irritability, restlessness, and abdominal pain. Melatonin is generally well-tolerated and is considered safer than many other sleep medications with a low risk of dependence, tolerance, or rebound insomnia. If side effects persist or concern you, speak to your prescriber.
Is Melatonin addictive?
No, melatonin is not considered addictive and does not carry the dependence risk associated with benzodiazepines (such as diazepam or temazepam) or Z-drugs (such as zopiclone or zolpidem). You will not develop physical dependence or experience withdrawal symptoms when stopping melatonin. This is one of the key advantages of melatonin for insomnia management. However, it is still best used for the shortest duration necessary while addressing any underlying causes of poor sleep through good sleep hygiene practices.
What medications interact with Melatonin?
Melatonin has several drug interactions to be aware of. Fluvoxamine (an SSRI antidepressant) significantly increases melatonin levels and should generally be avoided together. Quinolone antibiotics (such as ciprofloxacin) and cimetidine may also increase melatonin levels. Carbamazepine and rifampicin may reduce melatonin’s effectiveness. Melatonin can enhance the sedative effects of benzodiazepines, Z-drugs, and antihistamines. Warfarin’s effects may be altered. Alcohol should be avoided as it impairs melatonin’s sleep-promoting effects and reduces natural melatonin production.
Can I drink alcohol while taking Melatonin?
It is best to avoid alcohol while taking melatonin. Alcohol reduces the effectiveness of melatonin and impairs natural melatonin production. It also disrupts sleep architecture, reducing the restorative deep-sleep stages. Combining alcohol with melatonin may increase drowsiness, dizziness, and impaired concentration. If you are using melatonin to improve sleep quality, avoiding evening alcohol consumption will significantly improve your outcomes.
Can I take Melatonin during pregnancy or breastfeeding?
Melatonin is not recommended during pregnancy or breastfeeding due to insufficient safety data. Melatonin crosses the placenta and is excreted in breast milk. Although it is a naturally occurring hormone, the effects of supplemental doses on foetal development and breastfed infants are not well established. If you are pregnant, planning to become pregnant, or breastfeeding and struggling with sleep, speak to your doctor about non-pharmacological sleep strategies or alternative treatments that have better-established safety profiles.
How should I store Melatonin?
Store melatonin tablets below 25°C in the original packaging, away from moisture and direct light. Keep out of reach of children. Do not use melatonin tablets after the expiry date printed on the packaging. Return any unused or expired melatonin to your pharmacy for safe disposal. If you are travelling with melatonin, keep it in your hand luggage with a copy of your prescription, as melatonin regulations vary between countries.
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