Valproic acid

Valproic acidPrices, Coupons & Savings

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*Based on the difference between the U&C price submitted and the price the patient paid, as of April 2023.

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  2. Valproic Acid
    Generic for Depakene
    30 capsules $7.2 USD
    Save $133.20
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Do you need a prescription for valproic acid?

Yes, valproic acid is only available with a valid physician Rx.

How much is valproic acid without Insurance in the US?

Our website gives two competitive savings options to US customers who wish to purchase valproic acid, as either a brand or generic, if available. The first is access to medications through our mail-order online pharmacy. The second is by using the Now Patient Rx Advantage Card, which can be used in over 65,000 pharmacies nationwide, across America. If you are insured, then in most cases, the cash price will be significantly cheaper than the copay.

What will my out-of-pocket cost be for valproic acid in the US?

There are no out-of-pocket (OOP) costs because we are currently only offering a cash-based option to purchase medications.

Is Now Patient a valproic acid savings card?

Yes. Save up to 90% on your valproic acid with the FREE Now Patient Rx Advantage card*.
*Based on the difference between the U&C submitted by the pharmacy and the price the patients pay.

Can you handle Rx transfers for home delivery in the US?

Yes. If you use the mail-order online pharmacy option, then we can handle requests by you to have your prescription transferred to our pharmacy for home delivery. We can even help you manage your refills by giving you timely reminders, so you do not run out of your medication.

Is Now Patient a valproic acid coupon provider in the US?

No. Now Patient does not provide valproic acid coupons or FREE valproic acid samples.

Do you accept commercial, Medicare or Medicaid coverage for valproic acid in the US?

No. Currently, we only offer cash-based options for purchase, therefore we do not require your insurance benefit details. In the future, our plan is to be able to handle commercial insurance, Medicare and Medicaid including cases where you have multiple health plans that provide benefit coverage (e.g. Medicaid and Commercial). We also anticipate being able to handle more complex scenarios such as using primary insurance combined with a manufacturer copay assistance program.

Does Now Patient work with Medicare?

Our cash-based prices for medications are typically cheaper than Medicare copays. We do not bill Medicare Part D (standalone drug coverage) or Medicare Advantage (combined health and drug coverage). When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

Does Now Patient work with Commercial Insurance?

Our cash-based prices for medications are typically cheaper than commercial plan copays. We do not bill your commercial plan. When you purchase your medication from Now Patient, you will be doing so out of your pocket. The spend will not count towards your plan deductibles or gaps.

What should you do if you use too much valproic acid?


Call your doctor right away or seek immediate medical attention if your symptoms do not improve or they become worse after using valproic acid. You can also call 800-222-1222 to reach the American Association of Poison Control Centers or use its online resource if you think you’ve used too much valproic acid. But if you have severe symptoms, call 911 (or your local emergency number) immediately or go to the nearest emergency room.


If you think it is an emergency, call 999 or find your nearest A&E
If you need help now, but it’s not an emergency go to 111.nhs.uk or call 111. Alternatively you can speak to one of our pharmacists or use the Now Patient app to make an appointment with your GP.

What should I do if I miss my dose?

There are occasions when people forget to take their medication at correct prescribed times. This may not only have an effect on potentially making the medication less effective but it may also inadvertently lead to taking doses too close together, thereby increasing the risks of side effects.

Click here to find out what to do if you forgot to take your medication

What is generic valproic acid?

Generic valproic acid (VPA) refers to the non-brand-name version of the medication. It contains the same active ingredient as the brand-name drug but is typically less expensive.

FDA approval of valproic acid

Valproic acid is approved by the U.S. Food and Drug Administration (FDA) for various indications, including the treatment of epilepsy, bipolar disorder, and migraine headaches.

Active ingredient of valproic acid

The active ingredient of valproic acid is valproic acid.

US brand name of valproic acid and manufacturer

Valproic acid is available in the US under various brand names, including Depakene, Belvo, Depakote, and Syonell. The manufacturers may vary depending on the brand names.

UK brand name of valproic acid and manufacturer

In the UK, valproic acid is available under various brand names, including Convulex. The manufacturer may vary depending on the brand name.

Prescription requirement for valproic acid

A prescription (Rx) is required for valproic acid in both the US and the UK.

Availability of valproic acid in the UK with NHS prescription

Valproic acid is available in the UK with an NHS prescription.

Conditions treated by valproic acid

Valproic acid is an anticonvulsant/antiepileptic drug used for the treatment of epilepsy (types of seizure disorders), as monotherapy and adjunctive therapy for absence seizures and complex partial seizures. It may also be used in patients who have acute manic or mixed episodes associated with bipolar disorder. Occasionally it may be used to prevent migraine headaches.

How does valproic acid work?

The exact mechanism of action of valproic acid is not fully understood. It is believed to work by increasing the levels of certain chemicals in the brain that help to regulate electrical activity and stabilize mood.

Forms of valproic acid available

Valproic acid is available in various formulations, including oral capsules, extended-release tablets, delayed-release tablets, sprinkle capsules, and syrup (liquid).

Dosage of valproic acid

The dosage of valproic acid may vary depending on the specific condition being treated, the severity of the condition, and other individual factors. It is important to follow the recommended dosage instructions provided by the healthcare provider.

Directions for valproic acid use

Valproic acid should be taken or administered as directed by the healthcare provider. The specific instructions may include the timing of administration, dosage adjustments, and any necessary precautions.

Warnings and precautions for valproic acid

  • Valproic acid may cause serious side effects, including hepatotoxicity, pancreatitis (inflammation of the pancreas), birth defects (oral clefts, spina bifida, cardiovascular and limb malformations), hyperammonemia, encephalopathy, CNS depression (which may impair your ability to perform physical or mental tasks), and suicidal thoughts and behaviour
  • Regular monitoring of liver function and blood cell counts may be required during treatment with valproic acid
  • Tell your doctor if you have a rare metabolic condition such as Alpers Huttenlocher Syndrome, urea cycle disorder, mitochondrial disorder, or liver disease
  • Valproic acid is not recommended for use in pregnant women as it may cause fetal harm (teratogenic). Women of a childbearing age should speak to their doctor before starting treatment
  • Valproic acid passes into breast milk. Speak to your doctor if you are breastfeeding

Use of valproic acid if pregnant or planning pregnancy

Valproic acid can cause serious birth defects and developmental disorders. It should not be used during pregnancy unless there are no other suitable treatment options available. Women of childbearing age should use effective contraception while taking valproic acid.

Possible side effects of valproic acid

Common side effects of valproic acid may include weight gain, hair loss, nausea, vomiting, drowsiness, dizziness, and tremor. Serious side effects such as hepatic toxicity (liver failure) and suicidal thoughts are rare but can occur. It is important to promptly report any concerning symptoms to a healthcare provider. Get medical help right away if you have a life threatening allergic reaction. Symptoms include hives, trouble breathing, worsening shortness of breath, sore throat, chest pain, swelling of the face, tongue or throat, skin rash, blisters, and serious skin reactions.

Interactions with other drugs

Valproic acid may interact with other medications, including anticoagulants such as warfarin, clonazepam, ethosuximide, felbamate, certain hormonal contraceptives, phenobarbital, phenytoin, sedatives, topiramate, and zidovudine. It is important to inform your healthcare provider about all the prescription drugs, over the counter nonprescription medications, salt substitutes, herbal products, supplements, and vitamins you are taking to avoid potential adverse effects and drug interactions.

Similar drugs to valproic acid

Other antiepileptic medications, such as carbamazepine, phenyl and lamotrigine, may be used as alternatives to valproic acid for the treatment of epilepsy. For bipolar disorder and migraines, other mood stabilizers and migraine-specific medications may be considered. Divalproex sodium, valproate sodium, sodium valproate and semisodium valproate are similar medications to valproic acid.


About Now Patient

Now Patient’s online services are available in the US and UK. We help you manage your prescriptions, doctor appointments, test results, health risks, and a lot more, all in one place for FREE. If you are in the United States, you could enjoy savings using Now Patient’s mail-order pharmacy or use the Now Patient Rx Advantage Card at over 65,000 pharmacies, with savings of up to 90% on popular FDA-approved brand and generic medications like Ozempic, Mounjaro, clopidogrel and lots more. We do not currently handle commercial insurance, Medicare or Medicaid. UK NHS and private prescriptions are delivered FREE of charge across England & Wales by our UK NHS online pharmacy.

Stefano Mirabello Medical Reviewer
Pharmacist / B.Pharm
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